Gastrointestinal Flashcards
Describe the dietary changes expected of patients with liver cirrhosis.
Abstain from alcohol
High calorie diet, high carb, low fat
Do not restrict protein
Describe the medications to avoid when a person has liver cirrhosis.
Avoid hepatotoxic medications (Tylenol, Statins)
Avoid Aspirin and NSAIDs when portal HTN or varices are present (due to bleeding risk)
What activities should a patient with liver cirrhosis avoid?
Activities that increase intraabdominal pressure (straining, coughing, sneezing, vomiting, heavy lifting, tight clothing)
When should a patient with liver cirrhosis seek medication attention?
Presence of blood when vomiting
Bloody or black, tarry stools
Altered mental status (encephalopathy)
progressive, degenerative disease caused by destruction and subsequent disordered regeneration of the liver parenchyma
Liver cirrhosis
What is the typical protein intake recommended for patients with liver cirrhosis?
1.2-1.5g/kg
What two major issues are associated with hypomagnesia?
Ventricular arrhythmias - torsades the pointes
Neuromuscular excitability - similar to hypocalcemia (tremors, hyperactive reflex, positive Troussea and Chvostek, seizures)
What two complications are associated with hypercalcemia?
Constipation and polyuria (due to diuretic effect)
What type of history would be expected of a patient with hypomagnesia?
Alcohol abuse
inadequate nutritional intake
underlying GI or nephro issues
What is the action of misprostol?
Synthetic prostaglandin that protects against gastric ulcers by reducing stomach acid and promoting mucus production and cell regeneration
Misoprostol is often prescribed in patients to prevent gastric ulcers in clients receiving long-term _______ therapy
NSAID
What medication type can often increase adverse effects of misoprostol?
What should be done in these instances?
Antacids can increase the adverse effects - e.g. diarrhea and dehydration
if antacids are required, clients should receive those that do not contain magnesium (e.g. Tums)
What are instructions for the use of misoprostol?
Take with food to reduce side effects (abdo pain, cramping, diarrhea)
The drug is pregnancy category X - must discontinue if suspected pregnancy (med used for labour induction)
What is the indication for the use of sodium polystyrene sulfonate?
(Kayexelate) Administered to clients with hyperkalemia
What is the MOA of sodium polystyrene sulfonate?
Kayexelate resin replaces sodium ions for potassium ions in the large intestine and promotes evacuation of potassium-rich stool, thereby lowering serum potassium
What is a major side effect of sodium polystyrene sulfonate?
Intestinal necrosis
What is the purpose of the administration of neomycin enema?
Reduces the number of bacteria in the intestine in preparation for colon surgery
The client with liver cirrhosis is at risk for developing this neurological condition.
hepatic encephalopathy
What conditions/factors can predispose an individual with cirrhosis to hepatic encephalopathy?
Hypokalemia, high protein intake, GI bleeding, constipation, hypovolemia, infection
Low albumin is often expected in liver failure, but what is the purpose of albumin transfusions in this popuation?
Albumin is infused to promote good diuresis when used in combination with furosemide