Gastrointestinal Flashcards
What is the tonicity of saliva?
Hypotonic
What is the pH of saliva?
Usually alkaline, due to potassium and bicarbonate, can be from slightly acidic to pH 8
Contents of saliva (6)
Mucins Amylase Lingual lipase IgA Lysozyme Lactoferrin
Purpose of mucins?
lubrication
Function of saliva? (7)
Lubrication for speech Transmits infections Digestion Solvent for taste molecues Lubrication of food Dental hygiene Lysozyme to kill pathogens
What is Xerostomia?
Dry mouth, sign of dehydration
Location of salivary glands? (3)
Sublingual
Submandibular
Parotid
Location of entry of salivary ducts? (3)
Sublingual - lateral
Submandidular - medial
Parotid - opposite crown of 2nd upper molar tooth
Neural control of salivary glands (5)
Autonomic
Parasympathetic
Sympathetic causes slight increase in production but mostly vasconstriction
Sublingual and Submandibular - chorda tympani (CN VII)
Parotid - Glossopharyngeal (CN IX)
What effect would antimuscarinic drugs have?
Cause xerostomia
Stages of swallowing (3)
Oral preparatory phase
Pharyngeal phase
Oesophageal stage
Describe the oral preparatory phase? (3)
Voluntary (CN V3)
Pushes bolus to pharynx
Once bolus touches pharyngeal wall, pharyngeal phase starts
Describe the pharyngeal phase? (5)
Involuntary
Soft palate seals off nasopharynx (CN V3)
Larynx elevates closing epiglottis (Suprahyoid muscles)
Vocal cords adduct (CN X)
Opening of upper oesophageal sphincter
Describe the oesophageal phase? (3)
Involuntary
Closure of UOS
peristaltic wave caries bolus downwards
Main nerves involved in swallowing? (40
CN V3 (soft palate)
CN IX
CN X
CN XII (intrinsic muscles of the tongue)
How can babies eat and swallow at the same time?
Their epiglottis projects into the nasopharynx and their necks are shorter, meaning the epiglottis is always protecting the laryngeal inlet and the aspiration of fluid, but they can’t talk until epiglottis moves out of the way
Neural control of swallow and gag reflex? (5)
Mechanoreceptors at the back of the throat CN IX medulla CN X Pharyngeal constrictors
Which parts of the control of the head and neck are close in the brain?
Control of face and swallowing close so can both be affected
Describe the anatomical position of the oesophagus? (2)
Posterior to trachea
Right of aorta
Where does the narrowing of the oesophagus occur? (4)
UOS
Where aorta crosses oesophagus
where left main bronchus crosses the oesophagus
oesophageal hiatus where it passes through diaphragm
Prevention of gastro-oesophageal reflux (5)
LOS formed of smooth muscle
Diaphragm which causes narrowing of oesophagus
Intra-abdominal oesophagus compresses when intra-abdominal pressure rises
Mucosal rosette at cardia prevents backflow
actue angle of entry of oesophagus