Gastrointestinal Flashcards
Plummer-Vinson Syndrome
Esophageal webs, Fe+ def anemia, glossitis
Pt presents w/ Chest Pain, dysphagia, and odonophagia. His heart is fine. Dx?
Esophageal spasms! Do a barium swallow - will show corkscrew pattern
Pt comes in w/ odonophagia, large superficial lesions in his throat. Pathology - intranucleated and intracytoplasmic inclusions on biopsy. Dx/Dx?
CMV esophagitis
Tx: Gancyclovir
Zenkers Diverticula stick through what muscle?
The Cricopharyngeous muscle.
Pt. will have halitosis, and regurg of undigested food
Dx w/ barium swallow
Risk factors for esophageal SqCC and Adeno?
SqCC: smokin’ and drinkin’ (upper 2/3)
Adeno: GERD. popular in US (lower 1/3)
Why does esophageal CA metz early?
It has no serosa to hold it in!
What gastric hernia do you have to surgery for?
Paraesophageal (GE jxn stays put but the fundus herniates up through the LES)
Type A vs Type B gastritis
Type A: Fundus gastritis; due to Abs to parietal cells (shut down of this fxn will cause pernicious anema d/t lack of IF.) associated w/ Adeno CA & carcinoid tumors
Type B: Antrum gastritis; due to NSAIDs/H.pylori. Associated w/ PUD and Gastric CA
What is triple therapy for h.pylori?
Amox, Clarithro, PPI
What is the only CA that is cured w. Abx therapy?
MALT. It is a lymphoma that is associated w/ h. pylori
What type of gastric CA has signet cells?
Diffuse type. This has unknown cause.
Intestinal type is caused by h.pylori, nitrates, and no veggies. Does not have signet cells
What medication do you give to pts with PUD who have to take NSAIDs for coexisting arthritis or something
Misoprostal
Zollinger Edilsons Syndrome
A gastrin tumor (hi gastrin output) in duo/pancreas. Cuases increased gastric acid secretion and ulcers.
associated with MEN1
What are some organisms that cause bloody diarrhea?
Salmonella, Shigella, E coli (EHEC), and campylobacter
A guy goes camping and drinks from a nasty stream and then gets diarrhea. Dx? Tx?
Campylobacter - the poo will be bloody
Tx = Erythromycin.
What is the dreaded complication from c.diff diarrhea? How do you Dx c.diff colitis? Tx?
Toxic Megacolon
Dx c.diff colitis by checking for c.diff toxin in stool.
Tx: PO Metro or PO Vanc
Guy goes to mexico and drinks nasty water then gets diarrhea. What is the cause? What does endoscopy show? Tx? what drug is CONTRAINDICATED?
Entamoeba Histolytica
Endoscopy shows flask shaped ulcers
Tx = PO Metro
Don’t use steroids, you can get a FATAL PERFORATION
What is the treatment for E.Coli diarrhea 157:H7?
No therapy, just let it pass.
if you try and treat w/ Abx or antidiarrheals, you will increase the risk.
What is the main cause of osteomyelitis in sicklers?
Salmonella
What is the tx for salmonella OR shigella diarrhea?
TMP-SMX