Gastroenteritis Flashcards

1
Q

Gastroenteritis - background

A
  1. Def = inflammation of stomach and intestines. Typically results from bacterial toxins/viral infections. Results in vomiting and diarrhoea
  2. Usually viral in etiology (in children) - sudden in onset and quick to resolve
  3. Bacterial causes associated with more prolonged and severe illness
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2
Q

Viral gastroenteritis - background

A
  1. Transmission by oral-faecal route, including contaminated water
  2. Epidemics are frequent and usually occur during winter
  3. Breastfeeding protective; severity increased in malnourished children
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3
Q

Viral gastroenteritis - causes

A
  1. Rotavirus (most common)
  2. Norovirus
  3. Enteric adenovirus
  4. Astrovirus
  5. CMV (in immunocompromised pts)
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4
Q

Viral gastroenteritis - presentation (5+2)

A
  1. Watery diarrhoea (rarely bloody)
  2. Vomiting
  3. Cramping abdominal pain
  4. Fever
  5. Dehydration

+/- electrolyte disturbance
+/- URT signs common with rotavirus

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5
Q

Viral gastroenteritis - ix (2)

A

Rarely necessary, can do:

  1. Stool electron microscopy
  2. Stool immunoassay

If severe dehydration or altered conscious state:

  1. FBE
  2. UEC
  3. BGL
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6
Q

Gastroenteritis - ddx (3)

A
  1. UTI, other infections
  2. Appendicitis
  3. Surgical causes of acute abdomen
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7
Q

Gastroenteritis - mx

A
  1. Oral rehydration - with oral rehydration solution (cup, icypole, syringe). Trial in ED - aim for 10-20mL/kg fluid over 1hr of ORS. Continue breastfeeding. Usual diet once rehydrated.
  2. Nasogastric rehydration - if moderate dehydration, even if child is vomiting.
    a. For moderate dehydration, use rapid NG rehydration. 25mL/kg/hr for 4 hours
    b. If 30kg], not recommended for 10% dehydration or unable to tolerate oral fluids)
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8
Q

Bacterial gastroenteritis - background (3)

A
  1. Causes secretory and inflammatory diarrhoea
  2. Spread by faecal-oral route; sources of infection include contaminated water and poor food hygiene
  3. Common under 2y of age
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9
Q

Bacterial gastroenteritis - causative organisms

A
  1. Salmonella spp.
  2. Campylobacter jejuni
  3. Shigella spp
  4. Yersinia enterocolitica
  5. Escherichia coli
    +
  6. Clostridium difficile
  7. Bacillus cereus
  8. Vibrio cholerae
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10
Q

Bacterial gastroenteritis - presentation

A
  1. As for viral gastroenteritis (5 - diarrhoea, vomiting, abdominal pain, fever, dehydration)

Plus:

  1. Malaise
  2. Dysentry (bloody and mucous diarrhoea)
  3. Abdominal pain (may mimic appendicitis or IBD)
  4. Tenesmus
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11
Q

Bacterial gastroenteritis - complications

A
  1. Bacteraemia
  2. Secondary infections (esp. Salmonella, Campylobacter), e.g. pneumonia, osteomyelitis, meningitis
  3. Reiter’s syndrome (Shigella, Campylobacter)
  4. Haemolytic-uraemic syndrome (E. coli 0157 - enterohaemorrhagic, Shigella)
  5. Guillain-Barre syndrome (Campylobacter)
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12
Q

Bacterial gastroenteritis - ix

A
  1. Stool +/- blood culture
  2. Stool Clostridium difficile toxin
  3. Sigmoidoscopy if inflammatory bowel disease or colitis

If severe dehydration or altered conscious state:

  1. FBE, UEC
  2. BGL
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