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Block 11 module 3 > Gastroduodenal Tumors > Flashcards

Gastroduodenal Tumors Flashcards

1
Q

most common benign tumor of the stomach

A

Epithelial polyps

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2
Q

most common gastric polyp

A

Hyperplastic (regenerative

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3
Q

Three most common primary malignant gastric neoplasms

A

Adenocarcinoma (95%)
Lymphoma (4%)
Malignant Gastrointestinal Stromal Tumor (GIST) (1%)

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4
Q

most common genetic abnormalities in sporadic gastric cancer affect

A

p53 and COX-2 genes

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5
Q

Most common precursor of gastric CA the intestinal subtype

A

Atrophic Gastritis

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6
Q

common cell type arising in the stomach

A

Epithelial cell stromal GIST

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7
Q

most common site of duodenal CA

A

duodenal bulb

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8
Q

most common mesenchymal tumors in the small intestine

A

GI stromal tumors (GIST)

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9
Q

Five types of benign epithelial polyps

A

adenomatous, hyperplastic (regenerative), hamartomatous, inflammatory, and heterotopic

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10
Q

largest artery of the stomach

A

left gastric

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11
Q

where most of gastric CA arises

A

pyloric antrum

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12
Q

type of polyp that may undergo malignant transformation

A

adenomatous polyp

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13
Q

Benign submucosal fatty tumors that are usually asymptomatic, found incidentally on upper GI series or esophagogastroduodenoscopy (EGD)

A

lipoma

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14
Q

4 subtypes of gastric ca

A

polypoid
fungating
ulcerative
scirrhous

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15
Q

common presentation of Scirrhous type

A

Linitis Plasctica

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16
Q

gold standard for diagnostic evaluation of gastric ca

A

UGIE

17
Q

to demonstrate the depth of the tumor in terms of its involvement in relation to the layers of abdominal wall; more sensitive than CT scan in local staging;

A

Endoscopic UTZ

18
Q

• Generally accepted universal precursor to gastric adenocarcinoma

A

Dysplasia

19
Q

Examines extent of invasion of tumor and involvement of lymph nodes

A

EUS (Endoscopic Ultrasonography

20
Q

BEST WAY to stage tumor LOCALLY because it has 80% validity in assessing depth of tumor penetration

A

EUS (Endoscopic Ultrasonography)

21
Q

when is PET scan best used

A

If gastric CA has distant mestatasis

22
Q

Gold standard treatment for gastric Ca

A

Radical Subtotal Gastrectomy For Gastric Cancer

23
Q

INDICATIONS FOR SURGERY IN ADVANCE STAGE GASTRIC CANCER

A
  1. Perforation
  2. Obstruction
  3. Bleeding needing continuous transfusion
24
Q

mode of spread of gastric leiomyosarcoma

A

BLoodstream

25
Q

Malignant tumor of the smooth muscle

A

GASTRIC LEIOMYOSARCOMA

26
Q

where ampulla of vater is located in the duodenum

A

descending limb

27
Q

hypersecrete histamine

A

Enterochromaffin like cells (ecl)

28
Q

Patient swallows a capsule equipped with a camera which record images of the intestines

A

Capsule endoscopy

29
Q

Visualize layers of intestinal wall involved by the lesion

A

Endoscopic Ultrasound

30
Q

Whipple’s operation – resection of the

A 
Head of pancreas
Distal stomach
Duodenum
Gallbladder
Common bile duct
31
Q

gold standard test for helicobacter pylori

A

Histologic examination of an antral mucosal biopsy using special stains

32
Q

Useful in the evaluation of the patient with anomalous epigastric symptoms

A

Antrooduodenal Motility Testing and Electrogastrography

33
Q

alternative to Imatinib

A

Sunitinib

34
Q

tyrosine kinase inhibito

A

Imatinib

35
Q

lymphoma mostly occurs in the

A

ileum because it has the highest conc of lymphoid tissue

36
Q

most common site of GIST

A

stomach, SI 2nd

37
Q

classification of adenoma

A

tubula
villous
tubulovillous

38
Q

most agressive classificaiton of adenoma

A

villous

39
Q

high risk of developing hamartomatous polyps (have potentially malignant adenomatous foci)

A

Peutz-Jeghers Syndrome

Block 11 module 3 (2 decks)

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