Gastro Physio Flashcards
Sympathetic stimulations
slows/promotes GI motility
Slows
Dec motility
Dec secretions
Inc constriction of sphincters
Parasympathetic (acetylcholine)
Ince motility, secretion, dec constriction
Stretch of GI muscles: vagal stimulation
Inc secretions, inc motility, dec constriction
Exocrine gland secretes into
Duct
Endocrine secretes into
Blood
Paracrine cells
Cell next to it (cell to cell)
secretin
Produces bicarb from pancreas and liver
80-90% of pnacreatic cells secretes bicarb
Inhibits acid
CCK
When fat reached duodenum, makes pancreas secrete lipase and GB secrete Bile
Nunber 1 stimulus for gastrin secretion
Stomach distention
Fluid formation from an acinus to make saliva is what kind of pump?
Chloride Pump
Parasympathetic and Sympathetic both stimulate salivary secretions T/F
True
Parasympathetic: thinner and more quantity
Saliva has was kind of immunoglobulin
IgA
Dry eyes, dry mouth, dyspareunia
Sjorgen’s
Chief cells secrete
Pepsin
Parietal cells
Intrinsic factor, HCl,
IF combines with Vitamin what?
B12
Vitamin B12 is reabsorbed in the
Distal ileum
Mucous neck cells secrete
Bicarbonate
What anaemia develops from lack of Vitamin B12
Pernicious Anemia
inhibits parietal cell
Somatostatin
Site of si PPIs
hk-atpASE
CCK is secreted by
i CELLS
Increased in ZES
Gastrin
Gastrin is produced by
G cells
Cholecystokinin is produced by
I cells in the duodenum, jejunum
Secretin is produced by
S CELLS IN THE Duodenum
Action of Secretin
Inc pancreatic bicarb excretion, dec gastrin
Somatostatin is produced by
D cells of pancreatic islets
Action of Somatostatin
dec all secretions
3 that stimulate gastric parietal cell
Ach, Gastrin ), Histamine (act cAMP)
Only gland Located at the duodenal mucosa
Brunner’s gland
Trypsinogen is activated by
enterokinase/enteropeptidase
Absorption sites
Iron
Folate
B12
Iron Duodenum
Folate B9 Jejunum
B12 Cobalamin Ileum
encapsulated lymphoid tissue found in the lamina propria that has M cells taking up antigen and B cells that secrete IgA
Peyer’s Patience has to
Urobilinogen releases in the faces as _____ which is responsible for feces color
Stercobilin