Gastro Anatomy & Physiology Flashcards
Absorption site of Iron?
Duodenum & proximal jejunum
Absorption site for Vitamin B 12 &Bile salt ?
Terminal ileum
Factors that inhibit Gastric acid secretion ?
/ Somatostatin
/ CCK
/ Secretin
/ VIP
/ GIP
/ GLP-1
Name the satiety centre?
Ventromedial nucleus of Hypothalamus
Name the feeding centre?
Lateral hypothalamic area
Location of parietal cell?
Gastric body & secrets HCl & Intrinsic factor
Location of chief cell?
Gastric body & secretes Pepsinogen
Location of G cell?
Gastric antrum & secretes Gastrin
Hormones that modulate satiety?
- CCK
- Peptide YY
Hormones that enhanced satiety?
- GIP
- GLP-1
Hormones that stimulate appetite ?
- Ghrelin
- Neuropeptide Y
Hormones that decrease appetite ?
- Leptin
- Propiomelanocortin (POMC)
- Insulin
- GLP 1
Factors that Increase HCl secretion?
- Gastrin
- Ghrelin
- Acetylcholine
- Histamine
- Gastric distension
Factors that decrease HCl secretion ?
- CCK
- Secretin
- Somatostatin
- GIP
- GLP 1
- Low pH
- VIP
- Atropine
- Prostaglandin
Substance that are absorbed by Na+ dependent co transport ?
- Glucose / Galactose
- Amino acid
- Water soluble vitamins
- Bile acid
What are the GI Neurocrines ?
- VIP
- Neuropeptide Y
- NO
- GRP (Bombesin)
- Enkephalins
How glucose is transported from intestinal lumen to cell?
By Na+ dependent co transport (SGLT 1)
How glucose is absorbed from cell to blood?
By facilitated diffusion
Key stimulus for Gastric secretion?
Gastrin, Histamin & Acetylcholine
Hydrogen ion and Chloride ions are secreted from?
Apical membrane of gastric parietal cell into the lumen of the stomach by a Hydrogen-Potassium adenosine triphosphate (ATPase) ( Proton pump )
Which gland secretes ghrelin?
Oxyntic gland
What are the protective factors of Gastroduodenal mucosa?
- Bicarbonate ions, stimulated by Prostaglandin
- Mucin
- Trefoil factor family (TFF) peptide