Gastro

Question 1

recommended weekly alcohol unit for men and women

Answer 1

<14 units.

These 14 units should be spread evenly over atleast 3 days

Question 2

alcoholic hepatitis transaminases

Answer 2

AST:ALT > 2:1
elevated GGT

Question 3

How long after alcohol cessation to withdrawal

Answer 3

6-12 hrs

Question 4

Classic tetrad of symptoms whipple’s disease

Answer 4

• weight loss
• diarrhoea
  -colicky abdominal pain
• polyathralgia

BUT can be MULTISYSTEMIC

rarely no GI symptoms and only pc m’b seronegative polyathritis

Question 5

Main diagnostic procedure for whipples

Answer 5

jejunal biopsy: tissue macrophages are PAS poistive

Question 6

Extra-intestinal features of familial adenomatous polyposis

Answer 6

Turcot syndrome: FAP + brain tumours (glioma, medulloblastoma)

Gardner’s syndrome: FAP + desmoids, osteomas, and epidermoid cysts, fibromas, sebaceous cysts, supranumeery teeth

Question 7

Features of Cowden’s disease

Answer 7

Harmatomas in BOWEL thyroid, breast, uterus brain.
also skin manifestations: harmatomas of skin and mucosa, trichelomas, sclerotic fibromas