Gastric motility Flashcards
Transit time
time taken by food to travel from one location in gut to another
- increased in propulsive motility shortens transit time
- increased in retentive motility increases transit time
Functions of GI movements
- to propel ingesta from one location to the next
- to retain ingesta at a given site for digestion, absorption or storage
- to break up food material pysically and mix it with digestive secretions
- to circulate ingesta so that all portions come into contact with absorptive surfaces
GI SM cells are _______________ via gap junctions
electrically coupled
-allows transmission of depolarizations from cell to cell
GI pace maker cells are called?
interstitial cells of cajal
Interstitial cells of cajal are?
intrinsically rhythmic- repeatedly depolarize and then repolarize
Slow waves
initiated by ICCs propagate through GI smooth muscle as waves of subthreshold depolarization
-APs do NOT fire and contraction does NOT occue
Slow waves determine _________ of contraction._______ determine whether the contraction occurs or not
pattern
neurotransmitters
Pacemakers (ICCs) are located in or near SM in?
stomach
duodenum
colon
Peristaltic reflex is entirely internal to?
the ENS
Motility in the GI tract
mouth, pharynx, larynx -skeletal muscle -controlled by CNS esophagus -skeletal m (ruminants, dogs) CNS -mixed (cats, horses): ENS ,ANS Stomach and intestines -SM -mostly controlled by ENS -coordination essential for function (gap junctions, intrinsic rhythm)
Voluntary and involuntary phase of deglutition (swallowing)
- voluntary - food is pushed into oropharynx by the tongue
2. involuntary phase: swallowing reflex, controlled by CNS (cranial nerves V, VII, IX, X, XII)
Phases of swallowing include
- oral: tongue forms bolus
2. pharyngeal: propulsion of bolus from base of tongue to larngopharynx ; epiglottis covers tracheal orifice