Gastric anatomy

Question 1

Gastric Mucosa

Answer 1

• Has 4 layers.
• Mucosa is composed of simple columnar epithelium and is folded = rugae.
• The epithelium extends downwards and forms gastric pits, which narrow to gastric glands.

Question 2

Gastric Pit - 4 types of exocrine cells.

Answer 2

1. Mucus cells - mucus
2. Parietal or oxyntic cells - HCl and intrinsic factor.
3. Chief cells - pepsinogen and gastric lipase.
4. Enteroendocrine cells - i.e. G-cells produce gastrin.

Question 3

Gastrin

Answer 3

Increases gastric secretions, motility and relax the pylori sphincter.

Question 4

Somatostatin

Answer 4

From D cells, inhibits gastrin release.