Gas Laws Flashcards
Charles’ Law
Volume of gas varies directly with the absolute temperature @ constant P
=> volume of a fixed mass of gas @ constant P increases as temp increases
What is the ideal gas law
PV = nRT
P1V1/T1 = P2V2/T2
What is Patm and Palv before inspiration
0
What is Pip before inspiration
- 4 mmHg
What is the functional residual capacity
Volume of air left in lungs after passive expiration
DURING INSPIRATION
- Patm
- Pip
- Ptp (Palv - Pip)
- 0
- Increasing as thorax expands
- increases above opposing inward lung recoil force causing expansion of lungs
What happens to Palv @ mid-inspiration
Becomes -ve - reaches -1 mmHg
What is tidal volume
Amount of air that flows into lungs during quiet breathing - 500 ml
END OF INSPIRATION
- Patm
- Pip
- Ptp
- Palv
- 0
- @ most -ve (-7 mmHg) due to max thorax volume
- = to opposing inward lung recoil force
- equilibrate with Patm
no air flows in or out of lungs
DURING EXPIRATION
- Patm
- Pip
- Ptp
- Palv
- 0
- Pip increases as chest wall recoils
- decreases below inward lung recoil force => decrease in lung volume
- Rises above Patm
Values for
- Palv
- Pip
When air flows out of the lungs
- Palv = 0
- Pip = -4mmHg
What is minute ventilation
Total ventilation per min
Tidal volume x resp rate (per min)
6000ml/min = 500ml x 12
What is alveolar ventilation
Portion of VE that reaches the alveoli
Remainder ventilates the conducting airways => not available for gas exchange
What is anatomic dead space
1 ml for every pound of BW
What is physiological dead space
Anatomic and any alveoli not involved in gas exchange
Alveolar ventilation (VA)
Total volume of fresh air entering the alveoli/min
=> portion of VE available for gas exchange
VA = VT - VD x f
= (500 - 150) x 12
= 4200 ml
VA is more important in effectiveness of gas exchange
What influence do breathing patterns have
Have a marked influence on VA and thus effectiveness of gas exchange
What is Dalton’s Law of partial pressures
Atm P = 760 mmHg
Each gas contributes to total P
Individual gas’ contribution is proportional to number of molecules
* In a mixture of gases, each gas exerts same pressure as if it filled the container alone
What does the equilibrium of gases imply
Rate of back diffusion = rate of diffusion of plasma => PO2 plasma = PO2 room air
Henry’s Law
When gas under pressure comes in contact with liquid, gas dissolves in liquid until equilibrium is reached
@ a given temp, amount of gas in solution is proportional to partial pressure of that gas
What is the magnitude of water vapour P proportional to
Temperature
@ body temp = 47 mmHg
Name gases in blood in terms of DECREASING solubility
- CO2
- O2
- N2
PO2
- Dry air
- Alveolar gas
- Arterial blood
- Mixed venous blood
- 159
- 104
- 100
- 40
PCO2
- Dry air
- Alveolar gas
- Arterial blood
- Mixed venous blood
- 0.03
- 40
- 40
- 46
PH2O - alveolar gas
47
P total
- Dry air
- Alveolar gas
- 760
- 760