Gas Exchange Flashcards

1
Q

Causes dilution of gasses in the upper resp

A

Humidification

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2
Q

Partial pressures of inspired air

A
Total 760
N2: 601
O2: 159
CO2 0.3
H20: variable
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3
Q

Occurs if humidification of air does not occur

A

Lung tissue damage or infection

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4
Q

Pp of H20 in alveoli

A

47 mm Hg

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5
Q

Pp flow of 02

A
o	159 mm inspired
o	105 alveoli
o	100 arterial
o	40 systemic tissue
o	40 veins
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6
Q

Pp flow of CO2

A
o	0.3 mm Inspired
o	40 alveoli
o	40 artery
o	45 systemic tissue
o	45 veins
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7
Q

Increased contact area with RBCs in alveolar capillaries

A

Thin walls

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8
Q

Layers of the resp membrane

A
  • Fluid + surfactant
  • Alveolar epithelium
  • Basement membrane of epithelium
  • Thin interstitial space
  • Basement membrane of capillary
    Capillary endothelium
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9
Q

Factors influencing diffusion across resp membrane

A
  • Thickness (edema, fibrosis)
  • Surface area
  • Diffusion constant (co2 more rapid than 02)
  • Pressure difference
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10
Q

Where oxygen is in transport

A
  • 98.5% hemoglobin

- 1.5% dissolved in blood

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11
Q

Where oxygen binds

A

To the heme (fe) group on hemoglobin, up to 4. Now oxyhemoglobin

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12
Q

02 sat in arteries compared to veins

A

100% art, 80% vein

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13
Q

The oxy chart shift to the right means….

A

More 02 removal

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14
Q

the oxy chart shift to the left means

A

Less 02 removal

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15
Q

Causes more 02 removal

A
  • Decrease in pH
  • Increase in temp
  • Increase in CO2
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16
Q

As it gets colder, oxygen is ________ to remove

A

harder

17
Q

Methods of CO2 transport

A
  • Bicarbonate (70%)
  • Hemoglobin (23%)
  • Blood (7%)
18
Q

Acidosis effect of nervous system

A

Depression of CNS

19
Q

Alkalosis effect of nervous system

A

Increased excitability of PNS

20
Q

Chemical buffer systems

A
  • Bicarbonate
  • Phosphate
  • Protein
21
Q

Line of Buffers

A
  • Chemical
  • Resp
  • Renal
22
Q

More CO2 causes ______ bicarbonate

A

More, but also releases a acid

23
Q

Phosphate buffer

A

More for intra/extracellular fluid than for blood

24
Q

Protein buffers

A
  • Includes hemoglobin
  • Carboxyl group gets rid of H+
  • Amino group accepts H+
  • These side chains are present on 27 amino acids
25
Q

How the kidney works

A
  • Can excrete either acids or bases

- Can produce bicarbonate

26
Q

Response time of resp system

A

Minutes to hours

27
Q

Response time of renal system

A

1-2 days

28
Q

Def of metabolic acid/alkalosis

A

Any cause other than resp

29
Q

Can cause costal breathing to dominate over diaphragmatic

A
  • Exercise
  • Abdominal pressures, fluids, or masses restrict movement
  • Pain with deep breaths
30
Q

Accessory muscles of breathing

A
  • Scalene
  • SCM
  • Pec minor
  • SA
  • Abdominal wall
31
Q

How do the accessory muscles increase depth of breathing?

A
  • Scalene/SCM: raise upper ribs/sternum
  • Pec min/SA: when scapula is fixed, lift the rib cage
  • Abdominal wall: Push diaphragm superiorly
32
Q

Functions of the thoracic wall

A
  • Protection
  • Resist negative pressure of lungs
  • Attachment + support of UE
  • Muscle attachment
33
Q

Location of kidneys

A

Posterior abdominal wall, T12-L3

34
Q

What kidney is slightly higher

A

Right