gas exchange Flashcards
what is ventilation?
breathing
what is the trachea?
wind pipe
what is the thoracic cavity?
space where the lungs are
explain the human gas exchange system
● as you breathe in, air enters trachea
● trachea splits into 2 bronchi
● each bronchus branches off into smaller tubes called bronchioles
● bronchioles end in small air sacs called alveoli
● ribcage, intercostal muscles and diaphragm work together to move air in and out
explain inspiration
● external intercostal and diaphragm muscle contract
● causes the ribcage to move upwards and outwards
● diaphragm contracts to flatten
● increasing volume of thoracic cavity
● as volume increases, lung pressure decreases (to below atmospheric pressure)
● air flows down the trachea and into lungs down pressure gradient
what does inspiration require?
energy (active)
explain expiration
● external intercostal and diaphragm muscles relax
● ribcage moves downward and inwards
● diaphragm becomes curved
● volume of thoracic cavity decreases, causing pressure to increase (to above atmospheric pressure)
● air forced down pressure gradient and out of lungs
what does expiration not require?
energy (passive)
explain forced expiration
● external intercostal muscles relax
● internal intercostal muscles contract
● pulling ribcage further down and in
● movement of 2 sets of intercostal muscles are antagonising
what are alveoli made from?
alveolar epithelium
what is the alveolar epithelium made of?
a single layer of thin, flat squamous cells
how does human gaseous exchange happens in the alveoli?
● oxygen diffuses out alveoli, across the alveolar epithelium and capillary endothelium
● into haemoglobin in red blood cells
● carbon dioxide diffuses from blood across capillary endothelium and alveolar epithelium and into alveoli and is breathed out
● movement happens down a diffusion gradient
what is the capillary endothelium?
type of epithelium that forms the capillary wall
how does human gaseous exchange happens in the alveoli? (simplified)
● oxygen - trachea - bronchi - bronchioles - alveoli
● happens down a pressure gradient
● alveoli - diffuse across alveolar epithelium and capillary endothelium - capillary - haemoglobin in blood
● happens down a diffusion gradient
how are alveoli adapted for gas exchange?
● short diffusion distance - alveolar epithelium is made of squamous cells (thin exchange surface)
● large surface area - large number of alveoli means there’s a large surface for gas exchange and folds in alveolar epithelium
● steep concentration gradient of O2 and CO2 between alveoli and capillaries
● capillaries give good blood supply
what is fick’s law?
surface area x difference in conc / diffusion distance
what is the composition of gases inhaled?
● higher conc of O2
● N2 stays the same
● lower conc of CO2
what is the composition of gases exhaled?
● lower conc of O2
● N2 stays the same
● higher conc of CO2
what is tidal volume?
● tidal volume is the volume of air in each breath
● average 0.4 - 0.5dm^3