gas concentration regulation Flashcards
Cellular respiration occurs in cells to…
provide energy for its function
Cells rely on…
continuous supply of oxygen and removal of carbon dioxide
what is the respiratory system responsible for?
Respiratory system responsible for taking in oxygen and excreting carbon dioxide from the body
movement of oxygen from lungs
Circulatory system carries oxygen from the lungs → cells; also takes away carbon dioxide and delivers to lungs → excretion
what cause air to move in and out of the lungs?
Diaphragm and intercostal muscles
what is the diaphragm stimulated by?
stimulated by impulses from phrenic nerve
what is the intercostal muscles stimulated by?
stimulated by intercostal nerves
what controls the nerve impulses for muscle contraction?
- are controlled by a respiratory centre in the medulla oblongata
- 2 regions: one controls expiration; one controls inspiration
- To coordinate breathing, messages need to pass back and forth between the neurons in these two regions
chemicals affecting breathing
- Conc. of O2 and CO2 affect breathing rate and depth
- Conc. of CO2 in the blood plasma affects the conc. of hydrogen ions (H+)
- When CO2 dissolves in water → forms carbonic acid, which breaks down readily to form H+ and bicarbonate ions
two types of chemoreceptors
peripheral and central
peripheral chemoreceptors
- Groups of cells within the walls of the aorta and carotid arteries
- Sensitive to changes in the conc. of O2, CO2, and H+ in blood plasma
- Known as aortic or carotid bodies
central chemoreceptors
- Located in the medulla oblongata
- Sensitive to changes in the conc. of CO2 in the blood and H+ in the CSF
- When stimulated, send a nerve impulse to the area of the respiratory center that regulates breathing
Oxygen concentration decrease
- As O2 is consumed by cells, it’s conc. in the blood begins to fall
- If conc. falls below normal while other factors are constant, breathing rate increasesNeeds to be significantly low levels to have a major stimulatory effect
oxygen concentration increase
- Large decrease in O2 conc. stimulates the peripheral chemoreceptors → nerve impulses are transmitted to respiratory centre
- Nerve impulses stimulate the transmission of messages → diaphragm and intercostal muscles → breathing rate and depth increases
Carbon dioxide concentration increase
- Small increases in the conc. of CO2 can cause a marked increase in the rate and depth of breathing
- Any increase in CO2 in the plasma is associated with the conc. of H+
- Increase in conc. of both chemicals in blood à stimulates central and peripheral chemoreceptorsChemoreceptors located in medulla oblongata are most sensitive to changes
- Nerve impulses → respiratory centre (medulla) → increase in breathing rate and depth
- Increase in breathing rate that occurs following an increase in CO2 conc. = produced by stimulation of aortic and carotid bodies
Major factor in the regulation of breathing rate
Carbon dioxide concentration
increase in hydrogen ion concentration
- As H+ conc. of blood increases, the pH decreases (more acidic)
- Decrease in pH directly stimulates chemoreceptors in the aortic and carotid bodies →transmits impulses to the respiratory centre → increase in breathing rate and depth
gas conc: stimulus
increase of H+ and CO2 (decrease of pH)
gas conc: receptors
central chemoreceptors in respiratory store, peripheral chemoreceptors of aortic and carotid bodies
gas conc: modulator
respiratory centre in medulla vis nerve impulses
gas conc: effectors
diaphragm, intercostal muscles
gas conc: responses
increase of stimulation of respiratory muscles (diaphragm and intercostals) causes an increase in breathing rate and depth
gas conc: feedback
decrease in CO2 and H+
voluntary control of breathing
- Voluntary control comes via connections from the cerebral cortex to descending tracts in the SC
- Bypasses the respiratory centre in the medulla oblongata
- Protective device enabling us to prevent irritating gases and water from entering the lungs
what does build up of CO2 do?
stimulates the inspiratory centre to send impulses to inspiratory muscles
Hyperventilation
extremely rapid and deep breathing; results in dizziness and fainting due to loss of CO2 from blood
what can stimulate hyperventilation?
Can be stimulated by severe pain or emotional stress
how to treat hyperventilation?
Usually corrects itself (reduction in CO2 means that the chemoreceptors are not stimulated, reducing rate and depth of breathing until CO2 returns to normal)
exercise and breathing
Contracting muscles cells require large amounts of oxygen → produce large amounts of carbon dioxide
- Rate and depth of breathing increases (take in more oxygen, remove more carbon dioxide)
- Increase in H+ ions also!