Gas Chromatography Flashcards
used to separate mixtures of compounds that are volatile or can be made volatile
Gas chromatography
types of gas chromatography
Gas-solid chromatography
gas-liquid chromatography
commonly used GC in clinical laboratories
GLC
What are the carrier gas used in GC
nitrogen
helium
argon
MS is used as detector
yes
commonly used to interface a GC or LC with an MS
direct infusion
most common form of ionization used in GC/MS
electron ionization (EI)
Two types of ionization for LC/MS
electrospray ionization (ESI)
atmospheric pressure chemical ionization (APCI)
“soft” ionization techniques that leave the molecular ion largely intact in the source
ESI
APCI
involves passing the LC effluent through a capillary to which a voltage has been applied
ESI