Gametogenesis Flashcards
What is a gamete?
Mature haploid germ cell
What is genesis?
Formation
When does gametogenesis occur?
At puberty, from birth, in utero
What chromosomes do the male have?
X and Y
What gene is found on the Y chromosome?
SRY gene
Where is the SRY gene found?
Pre sertoli cells
What does the SRY gene do?
Gives instruction to make sertoli cells
What other gene does SRY switch on?
Sox9
What does the Sox9 do?
Turns on testicular genes
When would it turn into ovaries?
After 11.3 dpc as Sox9 expression is not maintained
What genes are found in the female?
Wnt4 & Foxl2
Where are Wnt4 & Foxl2 found?
Expressed by granulosa cells
How are the female genes suppressed?
By the SRY
What endocrine features control testis development?
Leydig cells: androgens - Sertoli cells: AMH hormone
What does the AMH do?
Develops the seminiferous cords