Gametogenesis Flashcards

1
Q

development of female gamete

A

primordial germ cells migrate into ovary and undergo mitosis –> oogonium + mitosis –> primary oocyte

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2
Q

primary oocytes reside in _

A

follicles

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3
Q

primary oocytes are suspended in _

A

prophase, unless chosen for ovulation

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4
Q

primary oocyte chosen for ovulation

A

goes through first meiotic division –> secondary oocyte –> secondary oocyte will begin second division and be arrested at metaphase until fertilization

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5
Q

primordial follicle

A

ONE primary oocyte + surrounding epithelial cells

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6
Q

primordial follicles give rise to _

A

primary follicles –> secrete zone pellucida

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7
Q

antrium

A

fluid filled space that acts to expand diameter of follicle –> secondary follicle

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8
Q

formation of male spermatid

A

-spermatogonium undergo mitosis to become spermatocyte –> spermatocyte under goes two rounds of meiosis –> secondary spermatocyte –> spermatid

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9
Q

males produce spermatogonium _

A

throughout lifetime

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10
Q

spermatid to sperm

A

nucleus condenses to heterochromatin, centriole gives rise to microtubule tail, RER and golgi form the acrosome, mitochondria are concentrated in the middle

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11
Q

formation of corpus luteum

A

egg + mass of cumulus cells are ejected from the follicle for ovulation –> remnants of this collapsed follicle differentiate into corpus luteum

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12
Q

corpus luteum

A

produces estrogen + progesterone for the secretory stage

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13
Q

FSH

A

causes primary follicles to become secondary follicles

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14
Q

How many secondary follicles does FSH induce?

A

around 20-30 so some can stay back to secrete estrogen for development of endometriumm

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15
Q

How many secondary follicles does FSH induce?

A

around 20-30 so some can stay back to secrete estrogen for development of endometrium

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16
Q

proliferative phase

A

when layers of endometrium are built each montht

17
Q

progesterone from corpus luteum

A

cuts off LH production

18
Q

LH

A

aids in late stages of maturation of follicles; LH surge causes ovulation and also forms corpus luteum

19
Q

menstral phase

A

happens when corpus luteum degenerates, resulting in plummet of estrogen and progesterone resulting in degeneration of endometrial layer

20
Q

progesterone

A

maintains endometrium to support implantation

21
Q

changes before/during fertilization

A

as sperm approaches egg, there is an acrosome reaction –> enzymes in acrosome help sperm get through zona pellucida –> penetration –> when sperm makes contact, changes occur in zona pellucida to inhibit any other sperm from also fertilizing the egg –> attachment stimulates second meiotic division

22
Q

implanting blastocyst secretes _

A

hCG for maintenance of corpus luteum (so it can produce progesterone and estrogen to sustain functional layer of endometrium)

23
Q

implantation at _

A

day 6