Gallstone disease Flashcards
Risk factors for Gallstones
Female Fair Forty Fertile (pregnant, COCP) Fat
Gallstone composition
Bile pigment stones 5%
Cholesterol stones 20%
Mixed stones 75%
Cholesterol gallstones
Large
Often solitary
Pigment gallstone
Small
Fragile
Calcium bilirubinate
Associated with haemolysis
Mixed gallstones
Often multiple
Complications of gallstones
Biliary colic Acute cholecystitis Chronic cholecystitis Mirizzi's syndrome Obstructive jaundice Pancreatitis Cholangitis Gallstone ileus
Biliary colic pathogenesis
Gallstone impacted in neck of gallbladder (Hartmann’s pouch)
Gallbladder spasm
Biliary colic presentation
RUQ pain - radiates to back / scapula
Attacks < 6 hrs
Worse with fatty food
Sweating
Investigations for biliary colic
Urine - bilirubin
Bloods
US - acoustic shadow
Management of biliary colic
Conservative:
- Rehydrate
- Nil by mouth
- Analgesia
Surgical - laproscopic cholecystectomy
Acute cholecystitis pathogenesis
Gallstone impaction in Hartmann’s pouch
+ inflammation
+/- Empyema
Acute cholecystitis presentation
Contiuous RUQ pain
Radiates to right scapula + epigastrum
Fever
Vomiting
Acute cholecystitis examination findings
Local peritonsim RUQ
Tachycardia
Shallow breathing
Murphy’s sign
Acute cholecystitis investigations
Urine - bilirubin
↑WCC
US
MRCP (MRI cholangiopancreatography)
Conservative management of acute cholecystitis
Nil by mouth
Fluid resus