Gallbladder Diseases Flashcards

1
Q

Cholelithiasis
-Definition and Etiology

A
  • Definition: stones in the gallbladder
  • Etiology: impaired metabolism of cholesterol, bilirubin and bile acids
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2
Q

3 types of stones

A

cholesterol, pigmented and mixed

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3
Q

Cholelithiasis
-Risk factors

A

– Obesity
– Sex (female)
– Middle ages
– Use of oral contraception
– Rapid weight loss
– Indigenous American ethnicity
– Genetic predisposition
– Pancreatic or ileal disease

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4
Q

When does biliary colic occur?

A

Occurs 30 minutes to several hours after eating fatty meal

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5
Q

Cholelithiasis Manifestations

A

Usually asymptomatic
* Epigastric and right quadrant pain
* Intolerance to fatty foods
* Vague symptoms: heartburn, flatulence, epigastric discomfort, food intolerances (fats and cabbage)
* Biliary colic
* Jaundice (if in bile duct)

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6
Q

What does the severity of cholelithiasis manifestations depend on?

A

Severity depends on:
Movement of stones
Obstruction

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7
Q

Why are the patient’s jaudiced with cholelithiasis?

A

Bile cannot flow into duodenum

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8
Q

Why does patient have dark amber urine that foams when shaken?

A

Soluble bilirubin in urine

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9
Q

What causes clay colored stools?

A

Bilirubin does not reach small intestine to be converted into urobilinogen

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10
Q

What causes Steatorrhea?

A

No bile salts in duodenum, preventing fat digestion

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11
Q

Why do patients develop pruritis?

A

Deposit of bile salts into skin tissues

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12
Q

What causes intolerance to fatty foods?

A

No bile in small intestine to help with fat digestion

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13
Q

What causes bleeding tendencies?

A

Decreased absorption of vitamin K

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14
Q

Cholecystitis
-Etiology

A
  • Acute or chronic
  • Most often caused by a gallstone lodged in the cystic duct
  • Leads to distended and inflamed gallbladder
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15
Q

Cholecystitis
-common symptoms

A

Common to see: fever, leukocytosis, rebound tenderness, and guarding

  • Pain is similar to biliary colic or cholelithiasis issues
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16
Q

Cholecysitis
-Lab values

A

increased bilirubin and alk phosphate

17
Q

Gallbladder pharmacotherapy

A

Analgesic: Ketorolac (Toradol): Pain control

Antiemetics: Nausea and vomiting

Anticholinergics: Decrease gallbladder secretion and
stop smooth muscle spasms

Bile acids (rarely used): Dissolve stones