G&E: Inheritance Flashcards
Gene
A sequence of bases on a DNA molecule that codes for a protein, which results in a characteristic.
Allele
A different version of a gene.
Genotype
The genetic constitution of an organism - the alleles an organism has.
Phenotype
The expression of the genetic constitution and its interaction with the environment - an organism’s characteristics.
Dominant
An allele whose characteristics appears in the phenotype even when there’s only one copy.
Shown with a capital letter.
Recessive
An allele whose characteristics only appears in the phenotype if two copies are present.
Shown by lower case letters.
Codominant
Alleles that are both expressed in the phenotype - neither one is recessive.
Locus
The fixed position of a gene on a chromosome.
Alleles of a gene are found at the same locus on each chromosome.
Homozygote
An organism that carries two copies of the same allele.
Heterozygote
An organism that carries two different alleles.
Carrier
A person carrying an allele which is not expressed in the phenotype but that can be passed on to offspring.
Are humans diploid or haploid organisms?
Diploid
How many alleles do gametes have?
One allele.
How can you predict the genotypes and phenotypes of the offspring produced if two parents are crossed?
Genetic diagrams.
Monohybrid inheritance
The inheritence of a characteristic controlled by a single gene.
Describe sickle-cell anaemia and the alleles involved:
Codominant alleles.
Homozygous + normal haemoglobin = no disease
Homozygous + sickle haemoglobin = disease + all blood cells are sickle-shaped
Heterozygous = sickle-cell trait
F1
First generation from parents
F2
Offspring of first set of offspring.
What is the phenotypic ratio for:
- monohybrid
- homozygous dominant x homozygous recessive
F1 = all heterozygous offspring
F2 = 3 : 1 (dominant: recessive)
What is the phenotypic ration for:
- dihybrid?
- homozygous dominant x homozygous recessive?
F1 = all heterzygous offspring
F2 = 9 : 3 : 3 : 1
dominant both : dominant 1st recessive 2nd : recessive 1st dominant 2nd : recessive both.
What is the phenotypic ration for:
- codominant?
- homozygous for one allele x homozygous for the other allele?
F1 = all heterzygous offspring
F2 = 1 : 2 : 1
In what scenarios might you not get the expected phenotypic ratio?
Because of sex linkage, autosomal linkage or epistasis.