G-Bugs and Treatment - G-R

Question 1

Klebsiella pneumoniaePneumonia, bacteremia

Answer 1

Cephalosporin +/- aminoglycoside Aztreonam and quinolones for penicillin allergyImipenem for ESBL strains

Question 2

Escherichia coliETEC

Answer 2

Ciprofloxacin (if warranted)

Question 3

Escherichia coliEHEC

Answer 3

Contraindicated

Question 4

Escherichia coliHUS from EHEC

Answer 4

Eculizumab

Question 5

Escherichia coliEIEC

Answer 5

Fluoroquinolone (if warranted)

Question 6

Escherichia coliMeningitis

Answer 6

3rd-gen cephalosporin (ceftriaxone)

Question 7

Escherichia coliPneumonia

Answer 7

3rd-gen cephalosporin or fluoroquinolone

Question 8

Escherichia coliUTI (UPEC)

Answer 8

fluoroquinolone, TMP-SMX, or nitrofurantoin

Question 9

ShigellaBloody colitis

Answer 9

Fluoroquinolone (if warranted)3rd-gen cephalosporin for cipro resistance

Question 10

SalmonellaNontyphoidal

Answer 10

Fluoroquinolone (if warranted)Ceftriaxone in preg pts and children

Question 11

SalmonellaTyphoidal

Answer 11

Fluoroquinolone (adult), ceftriaxone (children)Azithromycin, chloramphenicol for resistance

Question 12

PseudomonasEndocarditis, bacteremia

Answer 12

Aminoglycoside + antipseudomonal b-lactam (piperacillin, ticarcillin, ceftazidime, cefepime, imipenem)

Question 13

PseudomonasMeningitis

Answer 13

Ceftazidime

Question 14

PseudomonasOsteomyelitis

Answer 14

beta-lactam, carbapenem or fluoroquinolone

Question 15

PseudomonasUTI

Answer 15

Aminoglycoside or fluoroquinolone

Question 16

PseudomonasPneumonia 1

Answer 16

Antipseudomonal beta-lactam+ antipseudomonal quinolone (ciprofloxacinand levofloxacin)

Question 17

PseudomonasPneumonia 2

Answer 17

Antipseudomonal beta-lactam + aminoglycoside

Question 18

PseudomonasPneumonia 3

Answer 18

Antipseudomonal quinolone + aminoglycoside

Question 19

VibriosCholera, parahaemolyticus

Answer 19

Fluids and electrolytes

Question 20

CampylobacterBloody diarrhea

Answer 20

Fluoroquinolone or azithromycin

Question 21

Helicobacter pyloriGastric ulcer

Answer 21

PPI + amoxicillin + clarithromycin

Question 22

Haemophilus influenzaeOtitis media

Answer 22

AmoxicillinMacrolide for Pen Allergy

Question 23

Haemophilus influenzaeMeningitis

Answer 23

CeftriaxoneReplaces ampicillin (resistance)

Question 24

Yersinia pestisPlague

Answer 24

Streptomycin (gentamicin)Doxy, chloramphenicol

Question 25

Bordetella pertussispertussis

Answer 25

Macrolide (historically erythromycin)TMP-SMX

Question 26

Pasteurella multocidacellulitis

Answer 26

amoxicillin-clavulanatePenicillin, doxy, fluoroquinolone

Question 27

Francisella tularensistularemia

Answer 27

Streptomycin (gentamicin)Cipro, doxy for nonsevere disease

Question 28

Legionella pneumophilaLegionnaires disease

Answer 28

Levofloxacin or azithromycin

Question 29

Legionella pneumophilatransplant pts

Answer 29

LevofloxacinMacrolides interfere with cyclosporine

Question 30

Brucella spp.brucellosis

Answer 30

Doxy + streptomycinDoxy + rifampin

Question 31

Bacteroides intraabdominal abscess

Answer 31

metronidazole

Question 32

HACEKEndocarditis

Answer 32

CeftriaxoneReplaces penicillin (resistance)