FUNDAMENTALS OF VIROLOGY

Question 1

A mature virus particle containing a nucleic acid core surrounded by a protein coat, with or without an envelope.

Answer 1

Virion

Question 1

The capsid symmetry is either:

Answer 1

• Helical
• Icosahedral
• Complex

Question 2

Environmentally stable to temperature, gastric acidity, proteases, detergents, drying

A. Naked virus
B. Enveloped virus

Answer 2

A. Naked virus

Question 3

Modifies cell membrane during replication; released by budding and occasionally, cell lysis:

A. Naked virus
B. Enveloped virus

Answer 3

B. Enveloped virus

Question 4

Can easily spread by fomites, hand-to-hand contact, dust, and small droplets; can dry out and retain infectivity

A. Naked virus
B. Enveloped virus

Answer 4

A. Naked virus

Question 5

Viruses can be visualized directly by:

Answer 5

Electron microscopy

Question 6

Virus size ranges from:

Answer 6

200-300 nm

Question 7

Largest DNA virus:

Answer 7

Poxviruses

Question 8

Largest RNA viruses labile:

Answer 8

Paramyxoviruses

Question 9

Smallest animal virus:

Answer 9

Parvovirus

Question 10

Taxonomic level: Order
Suffix: _____

Answer 10

-virales

Question 11

Taxonomic level: Family
Suffix: _____

Answer 11

-viridae

Question 12

Taxonomic level: Subfamily
Suffix: _____

Answer 12

-virinae

Question 13

Taxonomic level: Genus
Suffix: _____

Answer 13

-virus

Question 14

Enumerate the steps involved in a viral replication cycle:

Answer 14

1. Adsorption
2. Penetration
3. Uncoating
4. Synthesis
5. Assembly of virion
6. Release

mnemonic: “APUSAR”