Fundamentals of Histology

Question 1

What causes neutrophil infiltration?

Answer 1

Acute inflammation

Question 2

What causes macrophage infiltration?

Answer 2

Late acute inflammation, chronic inflammation including granulomas

Question 3

What causes lymphocyte infiltration?

Answer 3

Chronic inflammation, lymphoma

Question 4

What causes plasma cell infiltration?

Answer 4

Chronic inflammation, lymphoma

Question 5

What causes eosinophil infiltration?

Answer 5

Allergic reaction, parasitic infections, tumours

Question 6

Describe the histological features of squamous cell carcinomas

Answer 6

Keratin production, intracellular bridges, do not form glands

Question 7

Describe the histological features of adenocarcinomas

Answer 7

Gland formation, secretion of glandular fluid, mucin production

Question 8

State at least four common sites of squamous cell carcinomas

Answer 8

Skin, head and neck, upper and middle oesophagus, anus, cervix, vagina

Question 9

State at least 4 common sites of adenocarcinomas

Answer 9

Lung, breast, stomach, colon, pancreas

Question 10

What does Fontana stain for?

Answer 10

Melanin

Question 11

What does Prussian blue stain for?

Answer 11

Iron (used in haemochromatosis)

Question 12

What does Congo Red stain for?

Answer 12

Amyloid, with apple green birefringence

Question 13

What is the marker of lymphoid cells?

Answer 13

CD45

Question 14

What is the marker for epithelial cells?

Answer 14

Cytokeratin