Fundamentals Of Biochemical Reactions

Question 1

Competitive Inhibitor

Answer 1

Binding at: active site
Vmax: unchanged
Km: increased
Solution: increase substrate concentration

insert graph

Question 2

Uncompetitive inhibitor

Answer 2

Binds at: site other than active site at Enzyme-Substrate Complex
Vmax: decreases
Km: decreases by the same factor

Graph: parallel lines

Question 3

Noncompetitive Inhibitor

Answer 3

Binds at: non-active site at either enzyme or enzyme-substrate complex
Vmax: decreases
Km: unchanged