Functions Of Choroid And Aging Changes In The Uvea Flashcards

1
Q

Middle layer of the eye

A

Uvea

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2
Q

Three regions of uvea

A

Iris
Ciliary body
Choroid

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3
Q

Choroid extends from ______ to _______

A

Ora serata to optic nerve

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4
Q

Choroid is located betwee the _____ and the ______

A

Sclera and retina

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5
Q

What kind of choroid absorbs excess light

A

Darkly pigmented choroid

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6
Q

This membrane of the choroid fuses with the retina multi laminated sheet

A

Bruchs membrane

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7
Q

This type of choroid provides nutrients to and remove the waste products from outer retina

A

Vascular choroid

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8
Q

Watershed layer of the retina

A

Outer plexiform layer

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9
Q

What separates the outer retinal layer from the inner retinal layer

A

Outer plexiform layer

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10
Q

Layers of the retina in the fovea

A

Area devoid of vessels

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11
Q

What is the sole blood supply to the fovea avascular zone

A

Cchoriocapillaris

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12
Q

Provides a pathway for the posterior vessels that supply the anterior segment

A

Suprachoroidal space of choroid

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13
Q

________ nerve carries sensory and sympathetic fibers

A

Long ciliary nerve

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14
Q

_____nerves carry sympathetic and parasympathetic fibers

A

Short ciliary nerves

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15
Q

Choroid changes in emmetropization: hyperopia refocus

A

Thin choroid, growth increased
-can rapidly modulate its thickness, in so doing, varying the position of the retina and thus the state of focus of the eye

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16
Q

Choroidal changes in emmetropization in myopic defocus

A

Thick choroid, growth decreased

17
Q

Functions of choroid

A

Provide nutrients and remove the waste products from outer retina

Passage of nerves and vessels

Absorption of excess light

Regulate emmetropization

18
Q

Aging changes in iris

A

Loss of pigmentation
Dilator muscle beceoms atrophic
Sphincter muscle becomes sclerotic

Difficult to dilate elderly

19
Q

Aqueous humor and age

A

Decreases, by 80, approximately 25% of what it was

20
Q

Aginging changes in choroid

A
  • choroicapillaris decreases in density and diamter, then choroidal blood flow decreases
  • bruchs membrane increases in thickness
  • various substances and particles accumulates in bruchs membrane
21
Q

Nutrients from the choriocapillaris and waste produce from the retina must pass though

A

Bruchs membrane

22
Q

Layers of bruches membrane

A
  1. Interrupted BM
  2. Outer collagenous zone
  3. Elastic layer
  4. Inner collagenous zone
  5. BM of RPE cels
23
Q

Calidification and the yellow deposits in the inner collagenous layer of Bruchs membrane. Made of the remaining cells (lipofuschin) from oxidative stress

A

Drusen

24
Q

Hello brown pigment granules composed of lipid containing residues from oxidativestress

A

Lipofuscin

25
Q

Accumulation of Drusen in Bruchs

A

Makes bruchs hydrophobic and presents a barrier to water movement, inhibiting the passing of metabolites
-water accumulation between RPE and Bruch’s membrane cause detachment

26
Q

AMD causes

A

Age, genetics, lifestyle
DRY
-extensive soft confluent Drusen throughout the macula with subtle RPE drop out
EARLY WET
-acute subretinal blood in macular area with subtle sub-retinal fluid; choroidal neovascularization membrane (CNVM) is not clearly visualized
LATE WET
-subretinal blood, CNVM and sub retinal fibrosis with RPE atrophy in macular area

27
Q

Which layer is multilaminated sheet and fuses with RPE

A

Bruchs membrane

28
Q

Which one proves blood to fovea region

A

Choriocapillaris

29
Q

Which part of retina receives blood supply from choroid

A

Outer retina

30
Q

Which layer of choroid proves a pathway for the vessels and nerves that supply the anterior segment

A

Suprachoriudal space

31
Q

Which change to bruchs membrane with aging (thickness)

A

Increases

32
Q

Which layer of bruchs membrane does druse deposit

A

Inner collagenous zone