Functioning of the Rods Flashcards

1
Q

Rods:

Pigment rhodopsin bleaches to form 2 chemical components;

A

Opsin and retinal.

These revert back to rhodopsin under low light intensity.

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2
Q

Rods:

There are 2 forms of retinal that are isomers of each other.

It is the retinal component which absorbs light.

Isomers have the same chemical formula but different structure.

A

Cis-retinal to trans-retinal under light.

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3
Q

Sequence of events when light hits the photochemical pigment in a rod:

  1. Light hits the ____
A

“rhodopsin molecule”.

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4
Q

Sequence of events when light hits the photochemical pigment in a rod:

  1. Within the rhodopsin molecule, cis-retinal is ____
A

“converted to trans-retinal”.

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5
Q

Sequence of events when light hits the photochemical pigment in a rod:

  1. Rhodopsin breaks down into its components, ____
A

“opsin and retinal”.

In darkness trans reverts to cis and rhodopsin is reformed.

DARK ADAPTATION
Mitochondria – ATP – rhodopsin resynthesis

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6
Q

Sequence of events when light hits the photochemical pigment in a rod:

  1. What is pumped out of the rod?
A

Na+ is pumped out of the rod and cannot diffuse back in rapidly – creates generator potential.

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7
Q

Sequence of events when light hits the photochemical pigment in a rod:

  1. When threshold is reached the inside of the rod becomes _____
A

“more negative ie, hyperpolarisation occurs”. (opposite to most receptors and neurones)

“Causes a change in the membrane potential.”

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8
Q

Sequence of events when light hits the photochemical pigment in a rod:

  1. Where does hyperpolarisation occur?
A

Hyperpolarisation occurs in the bipolar neurones.

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9
Q

Sequence of events when light hits the photochemical pigment in a rod:

  1. Where does depolarisation occur?
A

Depolarisation occurs in the ganglion cells sending an AP in the optic nerve.

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10
Q

What is the process of dark adaptation?

A

In the absence of light;
* trans-retinene is converted back to cis-retinene
* so the rhodopsin can be reformed.
* This is controlled by the enzyme retinene isomerase.

For this to occur all rods require ~30 minutes in the dark.

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11
Q

Dark adaptation:

In bright conditions, the cones work but the rods are ____

A

“bleached”
(rhodopsin is broken down).

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12
Q

Dark adaptation:

In dark conditions, the cones do not work but the rods ____

A

“can function if the rhodopsin molecules are intact”.

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13
Q

Dark adaptation:

When moving from bright to dark conditions, the rhodopsin must be ____

A

“reformed in the rods before they can work”.
Until this happens, temporary blindness results.

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14
Q

Dark adaptation:

The length of this period of blindness is the time taken for the ____

A

“rhodopsin to reform”
i.e., dark adaptation is occurring.

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