Fulminant Hepatic Failure Flashcards
1
Q
what is fulminant hepatic failure
A
Jaundice and encephalopathy in a patient with a previously normal liver.
2
Q
what are the common causes ?
A
Paracetamol Fulminant viral Drugs HBV Non A-E hepatitis
3
Q
what are the rare causes?
A
AFLP Mushrooms Malignancy Wilson’s Budd chiari HAV
4
Q
what are the signs of FHF?
A
- Encephalopathy
- Hypoglycaemia
- Coagulopathy- This is a defining feature of FHF
- Circulatory failure
- Renal Failure - creatinine starts rising
- Infection
5
Q
what do LFTs show?
A
hyperbilirubinaemia, elevated liver enzymes
6
Q
what do PTT show?
A
elevated - good marker for FHF
7
Q
what does metabolic panel show?
A
elevated urea and creatinine, weird K, PO4, and MG
8
Q
what maya FBC show?
A
leukocytosis, anaemia
9
Q
what maya ABG show?
A
metabolic acidosis
10
Q
what other tests would you do?
A
- serologies
- ceruloplasmin
- CXR - possible aspiration pneumonia
- USS
11
Q
what is the treatment?
A
supportive, inotropes and fluids, renal replacement management of ICP transplant
