Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

GI: liver, biliary tree and pancreas > Alcoholic Liver Disease and Consequences of Alcohol > Flashcards

Alcoholic Liver Disease and Consequences of Alcohol Flashcards

1
Q

what are the acute affects of alcohol on the GI system?

A

oesophagitis, gastritir/ulceration

acute pancreatitis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

what are the acute affects of alcohol on the respiratory system?

A

aspiration

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

which organs of the GI system are affected most by alcohol

A

liver, stomach and pancreas

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

what are the chronic affects of alcohol on the cardiovascular system?

A

Hypertension
Cardiomyopathy
Myocardial infarction
Stroke

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

what are the chronic affects of alcohol on the CNS system?

A

Neuropathies
Cerebellar degeneration
Dementia
Wernicke-Korsakoff’s syndrome

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

what are the chronic affects of alcohol on the haematologic system?

A

anaemia

bone marrow depression

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

what are the chronic affects of alcohol on the musculoskeletal system?

A

Proximal myopathy

Osteoporesis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Fatty alcoholic disease __%
Alcoholic hepatitis __-___%
cirrhotic changes __%

A

Fatty alcoholic disease 90%
Alcoholic hepatitis 10-30%
cirrhotic changes 30%

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

why is it called fatty liver disease?

A

When you consume alcohol it is metabolised into other toxic metabolites so there is increased peripheral release of fatty acids and increased synthesis of fatty acids and triglycerides within the liver cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

duration of drinking = 2-3 days

what is the change in the liver and is it reversible?

A

fatty liver - reversible

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

duration of drinking = 4-6 weeks

what is the change in the liver and is it reversible?

A

hepatitis - reversible

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

duration of drinking = months - years

what is the change in the liver and is it reversible?

A

fibrosis - irreversible

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

duration of drinking = years

what is the change in the liver and is it reversible?

A

cirrhosis - irreversible

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

what are the histological features of hepatitis - alcoholic

A

hepatocyte necrosis, neutrophils, mallory bodies and pericellular fibrosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

what are mallory bodies?

A

damaged intermediate filaments within the hepatocytes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

clinical spectrum of symptoms

A 
Malaise
Nausea
Hepatomegaly
Fever
Jaundice
Sepsis
Encephalopathy
Ascites
Renal Failure
Death
17
Q

what are biochem tests that indicate chronic liver disease?

A

prolonged prothrombin time, hypoalbuminaemia

18
Q

how is cirrhosis graded

A

Childs-turcotte - pugh

Or model for end stage liver disease

19
Q

biochem features of alcoholic hepatitis

A

Bilirubin > 80μmol/l

AST 1.5)

20
Q

if someone comes in with transaminases in the 1000 what is the likely cause of hepatitis

A

more likely drugs or viral cause

21
Q

what are the clinical features of alcoholic hepatitis?

A

hepatomegaly ± fever ± leucocytosis ± hepatic bruit

GI: liver, biliary tree and pancreas (20 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions