Frontotemporal Dementia (FTD)

Question 1

What is FTD?

Answer 1

progressive deficits in…
1. frontal lobe –> behaviour, executive function
2. temporal lobe –> language

Question 2

When is onset of FTD usually?

Answer 2

40-70 years old
RAPID!

Question 3

Is there treatment for FTD?

Answer 3

No cure

can manage behaviour symptoms with antidepressants or antipsychotics

Question 4

What are the two variants of FTD?

Answer 4

1. Behaviour Variant
2. Language Variant / “Primary Progressive Aphasia”

Question 5

Is there sub types to the Language variant of FTD? If so, what are they?

Answer 5

YES!

1. Semantic variant
2. Non-fluent variant

Question 6

What is behavioural FTD symptoms?

Answer 6

personality changes
beahvioural disinhibition
apathy

Question 7

What can behavioural disinhibition cause with FTD?

Answer 7

• tactless and socially inappropriate behaviour
• impulsive or careless actions (ex: reckless spending)
• new criminal behaviours
• embarassing personal remarks

Question 8

Reduced behavioural inhibition can lead to financial ruin. true or false

Answer 8

TRUE

Question 9

What is Language variant FTD?

Answer 9

progressive, insidious decline in linguistic skills
language deficits impairing daily functioning
aphasia

Question 10

What is the Semantic Variant FTD of the PPA?

Answer 10

deterioration in the ability to understand words and recognize objects

impaired confrontation naming (I show you a pic and you need to name what it is)

impaired single word comprehension

3 of :
- impaired object knowledge
- surface dyslexia (reading) or dysgraphia (writing)
- spared repetition
- spared speech production

Question 11

What is the Non-fluent variant FTD of the PPA?

Answer 11

deterioration in the ability to produce speech
one of:
- aggrammatism in production
- apraxia of speech (sequencing of speech, motor stuff)

two of:
- impaired comprehension of complex sentences
- spared single-word comprehension
-spared object knowledge

Question 12

What is the only risk factor known for FTD?

Answer 12

family history!

Question 13

What is the percentage prevalence of the population having Behavioural variant of FTD?

Answer 13

50-70%

Question 14

what is aggrammatism in production?

Answer 14

when you are not producing grammatical markers

Question 15

See table on slide 12 for diagnoses

Question 16

Look at tables with stats to find common things

Question 17

What two types of FTD do we see the most social problems occuring?

Answer 17

behavioural FTD

Semantic variant PPA

Question 18

When it comes to emotional problems, what type of FTD shows the most (apathy, low motivation, depression)?

Answer 18

Behavioural FTD

Question 19

What type of FTD rarely has problems with eating or oral behaviours?

Answer 19

Non-fluent variant of Language FTD/PPA

Question 20

What type of FTD rarely has sensory symptoms in diagnosis?

Answer 20

Non-fluent variant of Language FTD/PPA

Question 21

What type of FTD is most likely to have behavioural stereotypes in repetitive or compulsive behaviours?

Answer 21

Behavioural FTD

Question 22

What type of FTD has the most language symptoms?

Answer 22

Non-fluent variant of Language FTD/PPA

Question 23

What type of FTD is most likely to have problems with :
- impaired word finding
- impaired confrontation naming
- impaired single word comprehension
- surface dyslexia

Answer 23

Semantic variant of Language FTD/PPA

Question 24

What type of FTD is most likely to develop “prosopagnosia”?

Answer 24

Semantic variant of language FTD/PPA

Question 25

What is prosopagnosia?

Answer 25

when you have difficulty facial recognition

ex: they may recognize your voice but NOT your face

Question 26

What percentage of people diagnosed with FTD have no family history/gene mutation?

Answer 26

60-70%

Question 27

What percentage of people diagnosed with FTD have some family history/gene mutation of a neurodegenerative disease ?

Answer 27

20-25%

Question 28

What percentage of people diagnosed with FTD have strong family history/gene mutation?

Answer 28

10-15%