From Gred.ai Flashcards by Katherine Nutsch | Brainscape

Q

Liso-cel

A

JCAR 017
Large B-cell lymphoma (LBCL)
PFS: 12.6month (3rs rate = 50.9%) vs 6.2 month SOC (3yr = 26.5% SOC)
OS was 62.8% vs 51.8% SOC

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Q

Yescarta (Axi-cel)

A

Relapsed/refractory large B-cell Lymphoma (LBCL)
ZUMA-1: median PFS = 5.9 months vs ~3 month SOC chemo
OS = 12 months

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Q

Kymriah (Tisa-Cel)

A

Relapsed/refractory large B-cell Lymphoma (LBCL)
JULIET: PFS was ~3months, some up to 12months. OS 12-month = 52%
+ Pediatric Acute lymphocytic leukemia (ALL)

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Q

A

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Q

Abecma (idecabtagene vicleucel)

A

Muliple myeloma
KarMMa trial PFS = 8.8 months. SOC = 7.1 months, OS = 28 months
OS still being updated

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Q

A

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