Formulations Flashcards
Tablets
Hard formulations in which the drug and other ingredients are machine compressed under high pressure into a shape. most are for oral use
Capsules
Contains the drug and other ingredients packaged into a gelatin shell
Bulk powders
Contains the active drug in a small powder paper or foil envelope. the patient empties the envelope directly onto the back of their tongue and wash it down with a beverage or mixes it into said drink
Solutions
A clear non colorless liquid made up of one or more ingredients dissolved in a solvent
Aqeueos solution
Most common kind of oral solution. aqueous means that water was used as the solvent
Nonaqeuos solution
Solutions that are predominantly contains solvents other than water, either alone or in addition to water. Only a few nonaqeous solvents such as glycerin, alcohol, and propylene glycol can be used in oral solutions
Syrups
Concentrated or nearly saturated solutions of sucrose in water. They are thicker than water and contain less than 10% alcohol. Contain flavoring agents
Elixirs
Clear, sweetened, hydro alcoholic liquids intended for oral use. can contain either alcohol soluble or water soluble drugs. elixirs are usually less sweet and less viscous than syrups and less effective in masking taste. their alcohol content ranges from 5-40% (10-80 proof)
Spirits/Essences
Alcoholic or hydro alcoholic solutions of volatile substances (usually volatile oils) with alcohol contents ranging from 62-85% (124-170 proof). mostly used as flavoring agents but some spirits are used for their medicinal effects
Tinctures
Alcoholic or hydro alcoholic solutions of nonvolatile substances. tinctures of potent drugs contain 10g of the drug in each 100mL of tincture: they are called 10% tincture. nonpotent tinctures generally have 20g per 100mL of tincture and are called 20% tinctures
Suspensions
Formulations in which the drug does not completely dissolve in the solvent. the drug particles are suspended in the formulation. The primary concern when formulating suspensions is their tendency to settle over time leading to a lack of dose uniformity with a well formulated suspension either remaining suspended or settling very slowly and can be easily dispersed by shaking
Emulsions
Mixture of two liquids in which one liquid is dispersed through the other by mixing and using a stabilizer called an emulsifier
Gels
Made using substances called gelling agents which increase the viscosity of the medium in which they are placed and are most often added as an ingredient to liquid formulations
Suppositories
Semisolid dosage forms that dissolve or melt when inserted into the rectum
Intravenous
IV injections may be large volumes, slow infusion aqueous solutions or small volume single injections
Subcutaneous
SC injections generally provide slower absorption compared to IM administration but faster absorption than oral administration
Intramuscular
IM injections generally result in a slower onset but longer duration of action compared to IV administration
Intradermal
ID injections are administered into the top layer of skin at a slight angle using short needles
Syringes
used to inject formulations over a short period of time with the needle size being dependent on route of administration
Infusion
A gradual intravenous injection of a large volume of fluid (500mL to 1,000mL)
Z track injection
A technique used for medications which stain the skin or irritate tissues. wherein the skin is pulled to one side prior to injection the n the needle is inserted and the injection is preformed once the needle is removed the skin is released so that the injection points in the skin and muscle are no longer aligned thereby preventing the drug from entering the SC tissue and staining or irritating the skin. Z track injection is generally done 2 to 3 inched deep
Ointments
Contain drugs incorporated into a base
Creams
Semisolid emulsions which are less viscous and softer in texture than ointments with the added feature that they disappear with rubbing
Lotions
Suspensions of solid drugs in an aqueous vehicle
Pastes
Used for their protective action and for their ability to absorb secretions from skin lesions. Contains more solid matter than ointments and are stiffer and less penetrating
Plasters
Solid or semisolid adhesive masses which are spread on a suitable backing material and provide prolonged contact at site of application
Medicated dermal powders
A mixture of drug and an inert base with different dusting and covering capability