Formative Revision Quiz (canvas)

Question 1

Membrane receptors where the binding of an extracellular signalling molecule leads to changes in potential are called what?

Answer 1

Ligand-gated ion channels

Question 2

Define signal transduction

Answer 2

A séance of changes in a series of molecules that result in a response within the cell

Question 3

What would be the effect of a mutation on a G protein that prevented it from interacting with its G protein-couple receptor?

Answer 3

Unable to exchange GDP for GTP
G protein would reman inactive

Question 4

What type of protein family is involved in the activation of G proteins?

Answer 4

Guanosine nucleotide exchange proteins

Question 5

What type of protein family is involved in the deactivation of G proteins?

Answer 5

GTPase activating protein

Question 6

Second messengers are typically

Answer 6

Small, mobile molecules
Able to amplify signals
Able to diversify signals

Question 7

During the repolarisation phase of the cardiac action potential, the cardiomyocyte membrane is most permeable to which ion/s?

Answer 7

K+

Question 8

Intracellular receptors

Answer 8

Acts as transcriptional factors
Can found in either nucleus or cytoplasm in their inactive form

Question 9

Compound Z relaxed a constructed artery by acting on an enzyme in vascular smooth muscle cells. Compound Z may be:

Answer 9

Activating soluble guanylyl cyclase
A phosphodiesterase inhibitor
Activating protein kinase G

Question 10

A mutation in an SH2 domain that prevents it from interacting with its target protein is most likely to:

Answer 10

Inhibit cell proliferation
Disrupt signalling via activated growth factor receptors