Forebrain 1 Flashcards
How many layers are there in the neocortex?
6 layers
What is the functional unit of the cerebral cortex in most areas?
- A column of cells
- These extend through all the cortical layers
From which layer of the neocortex does the corticospinal axons arise from?
- Layer V (5)
These are quite large neurones (they have to go a long way)
Where is the functional organisation of columns best seen in the neocortex?
- Sensory Areas (E.g. primary visual cortex)
What does the neocortex include?
Most of the cortex except for:
- Olfactory Area
- Limbic Area
What are axons that leave the cerebral cortex called?
- Pyramidal Output Neurones
What happens to the number of interneurones & pyramidal nerves as we get smarter?
- Percentage of Pyramidal Neurones –> DECREASES
- Number of Stellate Interneurones –> INCREASES
What are the 2 important cell types in the cerebral cortex?
- Pyramidal Output Neurones
- Stellate Interneurones
What are the 4 main lobes of the cerebral hemisphere?
- Frontal
- Parietal
- Temporal
- Occipital
Why is the cerebral cortex arranged in columns (folds/gyri)?
- Increase Computing Power
- Folds allow you to increase the number of columns you can put
- Allows you to increase the area so you can increase the folds
NB: Most of the cerebral cortex (and brain) is surplus to requirements for basic survival (e.g. speech area)
What is the division between the frontal & parietal lobe?
- Central Sulcus
Infront –> FRONTAL LOBE
Behind –> PARIETAL LOBE
Describe tha path of the central sulcus?
- Runs from the midline
- All the way down to lateral side of the hemisphere
- It does not meet the lateral fissure (cut off by gyrus)
NB: The only sulcus which has a gyrus in front & behind it
How do you demarcate the occipital lobe?
- Poorly demarcated
- Best way is to go from notch to parietal-occipital sulcus (midline)
What is an extension of the central sulcus?
- Central Sulcus of Rolando
What is another name for the lateral fissure?
- Sylvian Fissure
What is the original structure that the cerebral hemispheres grow out of?
- Diencephalon
NB: Original diencephalon (not outgrowth) becomes the midbrain
Where is the 3rd ventricle found?
- Midline
How many horns does the lateral ventricle have and what are they called?
- Frontal Horn (into frontal lobe)
- Occipital Horn (into occipital lobe)
- Temporal Horn (into temporal lobe)
Where do the lateral ventricles open up to?
What is the hole that connects them called?
- Open up to 3rd ventricle
- Open up from both sides (into one 3rd ventricle)
- connect via the intraventricular foramen
Locate the following on this diagram:
- Lateral Fissure
- Lateral Ventricle
- 3rd Ventricle
- Temporal Lobe
- Gyrus
- Sulcus
What plane is this taken in?
- Coronal Section/Plane
Locate the Parieto-occipital sulcus on this diagram.
Can this be seen on the medial or lateral side?
What lobes are infront and behind the sulcus?
- Seen on the medial side
- Arbitrary on the lateral side
Infront of Sulcus –> Parietal Lobe
Behind Sulcus –> Occipital Lobe
What is the occipital lobe associated with?
- Vision
Locate the corpus callosum.
What is its main function?
- Great Commisure
- Main connection between both hemispheres
Axons cross the midline connecting both hemispheres
Where is the insular cortex found?
- Deep Cortex found Deep in the Lateral Fissure
- Embedded in the Floor of the Insular Cortex
Cannot see the insular cortex from the outside
what is the function of the insular cortex?
- Second Somatosensory Cortex Centre
- Important in Pain Sensation
What goes across (crosses over) the insular cortex that is very important?
Which fissure does this occur in?
- Middle Cerebral Artery (MCA)
It crosses over the insular cortex in the lateral fissure
Name the gyri which are pointed to here.
What happens to the gyri and sulci as you get older?
- Sulci –> WIDER
- Gyri –> THINNER
What is the gyrus in front of the central sulcus called?
- Pre-Central Gyrus
What are the 3 gyri on the lateral surface of the frontal lobe called?
- Superior Frontal Gyrus
- Middle Frontal Gyrus
- Inferior Frontal Gyrus
Describe the superior frontal gyrus?
- Wiggles up from the upper margin of the lateral surface of the frontal lobe
Describe the middle frontal gyrus?
- Wiggles along the side of the frontal lobe
- Continuous with the lower part of the pre-central gyrus (not shown in pic)
- Very convoluted
Describe the inferior frontal gyrus?
- Wiggles on the Top of the Lateral Fissure
- Highly convoluted
What are the 3 gyri of the lateral temporal lobe called?
- Superior Temporal Gyrus (easily seen)
- Middle Temporal Gyrus (easily seen)
- Inferior Temporal Gyrus (not easily seen)
NB: Sometimes ITG found on the underside
Where are the superior & inferior temporal sulci found?
Where is the post-central gyrus found?
- Behind the Central Sulcus
Where is the supramarginal gyrus found?
- Cuts off the end of the lateral fissure
Where is the angular gyrus found?
- Cuts off the end of the Superior Temporal Sulcus
Which gyrus cuts off the end of the lateral fissure?
- Supramarginal Gyrus
Where is the intraparietal sulcus found?
- Black line in image
What is the superior temporal sulcus walled off by?
- Cut off by the angular gyrus
Which lobe is the angular & supramarginal gyrus part of?
- Parietal Lobe
What is the paracentral lobule important for?
- Motor & Sensory Fibres of the Lower Limb
- Found either side of the central sulcus
What does the cingulate gyrus go around?
- Corpus Callosum
What is the uncus?
- Bump at the end
- Found on the medial side of the temporal lobe
What lobe is the parahippocampal gyrus part of
- Temporal Lobe
- Deepest part of temporal lobe
What is the calcarine sulcus important for?
- Important for demarcating the visual area
NB: Lots of visual information at occipital pole
Other structures of the brain.
Where is the fusiform gyrus?
What is it important for?
- Lateral to the Parahippocampal Gyrus
- Part of Temporal Lobe
- Found on the inferior surface of the temporal lobe
- Important for recognising things
What is brodmann’s area of the cerebral cortex based on?
- Based on Histology
- Histology reflects function
What two characteristics were used to divide brodmann areas up?
NB: Although the second one just happened to link to the first one
- Histology
- (reflects) Function
Cerebral Cortex divided into different (brodmann) areas –> due to different histology –> which happened to have different functions
Give 3 ways how functional localization in the cerebral cortex can be figured out.
- Pathology
- Stimulation (electrical)
- fMRI (functional MRI)
Where is broca’s area found?
- Left Hemisphere
- Dominant Side (usually left hemisphere only)
- V-Shape
Found just above the anterior part of the lateral fissure
What is found in broca’s area?
What is it needed for?
- Usually contains Language Centre
- Important in Fluent Speech
What is a sign of damage in Broca’s Area?
- If someone cannot give fluent speech
- Cannot speak
- They can however understand speech
- Regarded as a motor speech problem
Broca’s area is neccessary for fluent speech function
Why can electrical stimulation of the brain be done on conscious patients?
- There are no nociceptive receptors in the brain
- Only needs to be accessed using local anaesthetics
- Patients will not feel you poking/sucking things out from their head
NB: Some neurological surgeries are done under local anaesthetics to figure something out (e.g. keep talking to patient whilst working on broca’s area so that it is not affected)