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THE-PEAT Flash Card Study > Food and Drug Interactions > Flashcards

Food and Drug Interactions Flashcards

1
Q

Interaction: Statins and Grapefruit

A

Effect: Muscle pain and aches

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2
Q

Interaction: Antiplatelet drugs (Clopidogrel) NSAIDs (Aspirin Celecoxib Ibuprofen) Anticoagulant drugs (Warfarin Heparin)

A

Effects: all of these medications increase the risk of bleeding therefore combining them greatly increases risk of bleeding

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3
Q

Interaction: Multivalent ions (calcium, magnesium, iron, also in milk and antacids) + Levothyroxine Fluoroquinolones (Ciprofloxacin Moxifloxacin) Bisphosphonates (Alendronic acid {fosamax} Pamidronate {aredia}) Tetracyclines (Tetracycline Minocycline)

A

Effects: reduces the effectiveness of these drugs

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4
Q

Interaction: ACE inhibitors (Ramipril Lisinopril) + Potassium-elevating drugs

A

Effects: increase the risk of hyperkalemia

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5
Q

Interaction: Alpha-blockers + Antihypertensive drugs

A

Effect: dangerously low blood pressure.

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6
Q

Interaction: Aminoglycosides + Loop diuretics

A

Effects: increased risk of ototoxicity and kidney damage

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7
Q

Interaction: Antihistamines + Benzodiazepines SSRIs Antipsychotic drugs

A

Effects: increases the risk of sedation

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8
Q

Interaction: Beta-blockers + Calcium channel blockers

A

Effects: increases the risk of heart failure and a slow heart rate (bradycardia)

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9
Q

Interaction: Broad-spectrum antibiotics + Warfarin

A

Effects: increase the risk of bleeding with warfarin.

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10
Q

Interaction: Corticosteroids (Prednisolone Hydrocortisone) + NSAIDs

A

Effects: increase the risk of peptic ulceration and GI bleeding

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11
Q

Interaction: Corticosteroids + Beta-2 agonists Albuterol Terbutaline

A

Effect: increase the risk of hypokalemia

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12
Q

Interaction: Digoxin + Loop or thiazide diuretics

A

Effects: increased risk of digoxin toxicity

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13
Q

Interaction: Macrolides + Statins

A

Effect: increase the risk of adverse effects of statins

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14
Q

Interaction: Macrolides Amiodarone SSRIs Fluoroquinolones Quinine Antipsychotic drugs Quinine

A

Effects: increased risk of arrhythmias

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15
Q

Interaction: MAO inhibitors Isocarboxazid Tranylcypromine Phenelzine + Tyramine

A

Effect: increases the risk of hypertensive crisis (basically high BP –> stroke)

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16
Q

Interaction: Nitrates and PDE5 inhibitors

A

Effects: increased risk of severe hypotension

17
Q

Interaction: Omeprazole + Clopidogrel

A

Effect: reduces the antiplatelet effects of clopidogrel.

18
Q

Interaction: Phenytoin (dilantin) + Warfarin Estrogens (Progestogens)

A

Effect: reducing their clinical effects.

19
Q

Interaction: Ritonavir + Protease inhibitors Lopinavir

A

Effects: lower the needed dose of protease inhibitors

20
Q

Interaction: Sulfonylureas, Metformin, Thiazolidinediones

A

Effect: increases the risk of hypoglycemia

THE-PEAT Flash Card Study (6 decks)

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