FOM anki flashcards week 2

1
Q

What is the polarity of water?

A

Unequal electron sharing between hydrogen and oxygen leads to a dipole (partially positive H, partially negative O).

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2
Q

What structure does water have?

A

Water has a bent structure (tetrahedral bonding angle).

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3
Q

What are hydrogen bonds?

A

Bond between hydrogen (positive) and oxygen (negative) or other electronegative atoms. Essential for water’s properties.

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4
Q

How does the hydrophobic effect work?

A

Non-polar molecules aggregate in aqueous solutions (e.g., micelles, lipid bilayers).

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5
Q

Define amphipathic molecules.

A

Molecules with both hydrophilic and hydrophobic regions (e.g., phospholipids in cell membranes).

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6
Q

What is the primary function of cell membranes?

A

Selective barrier to the external environment, involved in signaling, transport, and recognition.

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7
Q

What is the basic structure of amino acids?

A

Alpha carbon bonded to amino group (-NH₂), carboxyl group (-COOH), hydrogen, and R group (side chain).

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8
Q

Classify amino acids.

A

Non-polar (hydrophobic), Polar (hydrophilic), Acidic (negative charge), Basic (positive charge).

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9
Q

How are peptide bonds formed?

A

Peptide bonds form through dehydration between amino acids, with partial double bond character.

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10
Q

Define protein primary structure.

A

Linear sequence of amino acids forming a polypeptide chain.

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11
Q

Describe the secondary structure of proteins.

A

Local folding of polypeptide backbone (alpha helix, beta-sheet, triple helix).

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12
Q

How is tertiary structure stabilized?

A

By hydrogen bonds, disulfide bridges, ionic interactions, and hydrophobic interactions.

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13
Q

What causes protein denaturation?

A

Disruption of secondary, tertiary, and quaternary structures due to heat, pH extremes, or chemicals.

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14
Q

Describe the quaternary structure of proteins.

A

Arrangement of multiple polypeptide subunits into a functional protein (e.g., hemoglobin).

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15
Q

What is the role of enzymes?

A

Biological catalysts that lower activation energy and increase the rate of biochemical reactions.

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16
Q

Describe Michaelis-Menten kinetics.

A

Relates reaction rate to substrate concentration, with Km (half-maximal velocity) and Vmax (maximum rate).

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17
Q

What are the types of enzyme inhibition?

A

Competitive, non-competitive, and uncompetitive inhibition.

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18
Q

What is the pH scale?

A

Measures H⁺ ion concentration, with pH = -log[H⁺].

19
Q

What does the Henderson-Hasselbalch equation describe?

A

Relates pH, pKa, and the ratio of acid to conjugate base concentrations.

20
Q

Explain the function of buffers.

A

Resist changes in pH by neutralizing added acids or bases.

21
Q

What is the isoelectric point?

A

pH at which an amino acid or protein has no net charge.

22
Q

How is oxygen transported in the blood?

A

Oxygen diffuses into blood in the alveoli, and hemoglobin carries it to tissues.

23
Q

Describe the structure of cell membranes.

A

A lipid bilayer with proteins and carbohydrates, containing amphipathic lipids.

24
Q

What is the role of the lymphatic system?

A

Transport excess fluid (lymph) and foreign bodies to lymph nodes for immune defense.

25
Q

How do veins and arteries differ?

A

Arteries carry blood away from the heart, veins carry blood back to the heart.

26
Q

What is the function of the gastrointestinal system?

A

Digests and absorbs nutrients, processes them in the liver.

27
Q

How does the respiratory system oxygenate blood?

A

Air enters the lungs, where oxygen diffuses into blood and is carried by hemoglobin.

28
Q

How do lymphatic vessels work?

A

Absorb excess tissue fluid and return it to the bloodstream as lymph.

29
Q

What is the function of skeletal muscles?

A

Muscles contract to produce movement at joints.

30
Q

What is the difference between fibrous, cartilaginous, and synovial joints?

A

Fibrous joints are least mobile, cartilaginous are intermediate, and synovial are most mobile.

31
Q

What are the features of synovial joints?

A

Include a fibrous capsule, synovial fluid, and articular cartilage; types include hinge, pivot, plane, ball and socket.

32
Q

What is the role of tendons?

A

Attach muscles to bones, facilitating movement.

33
Q

What is a reflex?

A

An involuntary response to a stimulus, tested in clinical exams.

34
Q

What is homeostasis?

A

The maintenance of a constant internal environment within a narrow range for survival.

35
Q

Describe feedback mechanisms in homeostasis.

A

Positive feedback amplifies changes (e.g., childbirth), negative feedback opposes changes (e.g., blood glucose regulation).

36
Q

How do X-rays work?

A

Use electric current to generate X-rays, which pass through the body; denser tissues absorb more.

37
Q

What are the strengths of CT scans?

A

Superior resolution for soft tissues, cross-sectional images.

38
Q

What are the weaknesses of MRI?

A

Expensive, time-consuming, and some patients experience claustrophobia.

39
Q

How does ultrasound work?

A

Uses sound waves to create 2D images, no ionizing radiation.

40
Q

Describe T1-weighted MRI imaging.

A

Tissues appear white with black details.

41
Q

How do bones develop?

A

Endochondral ossification turns cartilage into bone, especially in long bones.

42
Q

What are the types of fractures?

A

Fractures can be categorized by the type of break (e.g., simple, compound).

43
Q

Explain the structure of bones.

A

Composed of periosteum, epiphysis (growth ends), and diaphysis (shaft).