FOM

Question 1

What is homeopathy?

Answer 1

• giving medicine which contain no medicine
• recognise patients may choose complimentary and alternative medicines

Question 2

What is a drug?

Answer 2

• most drugs are chemically inert
• momentarily bind to command and control molecules in the body
• molecular structures are complementary receptors

Question 3

What is an agonist?

Answer 3

• binds to receptor and activates it signalling to produce a response

Question 4

What is affinity of a drug?

Answer 4

• extent to which a drug binds to its receptor at a given concentration

Question 5

What is the intrinsic activity of a drug?

Answer 5

• ability of drug to illicit an effect

Question 6

What does having a wide therapeutic index mean?

Answer 6

• very few people taking effective dose will experience toxic effects

Question 7

What is an antagonist?

Answer 7

• prevents response from occurring
• competitive and non-competitive
• has affinity for binding to receptor but does not evoke a response
• no efficacy/intrinsic activity

Question 8

What is the effect of competitive antagonist on potency?

Answer 8

• agonist has less potency

Question 9

Why is non-competitive antagonist irreversible?

Answer 9

• permanently bind on allosteric site
• no amount of agonist can compete and reverse effect
• effect stops when receptor is replaced or recycled

Question 10

What is pharmacological?

Answer 10

• antagonist acts at same target receptor as agonist

Question 11

What is a partial agonist?

Answer 11

• cannot produce a maximal response even when occupying 100% of receptors

Question 12

What are non-receptor drug targets?

Answer 12

• ion channels
• enzymes
• transporters

Question 13

What is tachyphylaxis?

Answer 13

• on repeated administration some drugs need increasing doses for same effect to occur