Foetal development Flashcards

1
Q

When does fertilisation take place after the menstrual period?

A

2 weeks after the menstrual period

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2
Q

From when can the fetal heart beat be detected?

A

6 weeks gestation

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3
Q

At how many weeks of gestation is the developing organism a fetus?

A

10 weeks

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4
Q

Where does exchange of nutrients between the maternal blood and fetal blood take place in the placenta?

A

Intervillous space

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5
Q

What is a miscarriage?

A

Spontaneous loss of pregnancy before 24 weeks, which is when the baby reaches viability

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6
Q

What is an early pregnancy loss?

A

Pregnancy loss occurring within 6/7 weeks before fetal heart beat is identified.
Gestational sac is seen but no baby.

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7
Q

What causes an early pregnancy loss?

A

Chromosomal problem such as aneuploidy

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8
Q

What causes a late pregnancy loss?

A

Infection, antiphospholipid syndrome

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9
Q

What causes biochemical loss?

A

Implantation failure

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10
Q

What are the risk factors for miscarriage?

A
  • gestational age - as the pregnancy progresses, the risk gets smaller
  • chromosomal abnormality
  • increasing maternal and paternal age
  • previous miscarriage
  • smoking, alcohol and excessive caffeine
  • pre-pregnancy weight
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11
Q

What is a threatened miscarriage?

A

Miscarriage has not happened, patient is experiencing vaginal bleeding

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12
Q

What is an inevitable miscarriage?

A

Cervix has opened and the fetus does not remain in the uterus

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13
Q

What is an incomplete miscarriage?

A

Some parts of the fetus have miscarriaged

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14
Q

What is a complete miscarriage?

A

All parts of the fetus have miscarriaged.

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15
Q

What is an anembryonic miscarriage?

A

No fetal pole, just gestational sac

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16
Q

What is a missed miscarriage?

A

Fetus has developed but there is no fetal heart

17
Q

When is the yolk sac seen within the gestational sac?

A

5 weeks

18
Q

How can you distinguish a pseudo sac from a gestational sac?

A

A pseudo sac does not contain a yolk sac

19
Q

Define recurrent miscarriage

A

Loss of three or more consecutive pregnancies

20
Q

How does antiphospholipid antibody cause recurrent miscarriage?

A

Inhibits trophoblast function by causing thrombosis in the small vessels and complement activation

21
Q

What is a hydatidiform mole?

A

Uncontrolled proliferation and invasion of trophoblast