FMS Flashcards

1
Q

Anabolism…
a) Mostly takes place in the mitochondria
b) Takes place in lipolysis
c) Mostly takes place in the cytosol
d) Takes place in glycolysis
e) Generates ATP

A

c) Mostly takes place in the cytosol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Which of the following is the correct “oxidation ladder” from most oxidised to least
oxidised?
a) Aldehydes, primary alcohol, alkanes, carboxylic acids
b) Carboxylic acids, primary alcohol, aldehydes, alkanes
c) Primary alcohol, aldehydes, carboxylic acids, alkanes
d) Carboxylic acids, aldehydes, primary alcohol, alkanes

A

d) Carboxylic acids, aldehydes, primary alcohol, alkanes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Which of these are all examples of catabolism?
a) Glycolysis, lipolysis, glycogenolysis
b) Glycolysis, lipogenesis, glycogenesis
c) Gluconeogenesis, lipolysis, glycogenesis
d) Gluconeogenesis, lipogenesis, glycogenesis
e) Gluconeogenesis, lipolysis, glycogenolysis

A

a) Glycolysis, lipolysis, glycogenolysis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Which of these is not a function of ATP?
a) They are used in sodium potassium pumps for active transport to occur
b) Endocytosis- transport of large molecules
c) Used in cell motility and contraction
d) Used in metabolism to add P to metabolic intermediate
e) A storage molecule for chemical energy

A

e) A storage molecule for chemical energy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

High concentrations of glucose-6-phosphate is inhibitory to which enzyme?
a) Glucokinase
b) Pyruvate kinase
c) Phosphofructokinase
d) Hexokinase
e) Aldolase

A

d) Hexokinase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

A young girl has come into hospital with diabetes mellites, after some blood work it is
suspected that she has a mutation in a gene for an enzyme which acts as a sensor for
blood glucose levels in the pancreatic β-cells. This enzyme is also involved in the
consumption of glucose in the liver. What is the enzyme which may have a mutation?
a) Hexokinase
b) Pyruvate kinase
c) Aldolase A
d) Glucokinase
e) Phosphoglucose isomerase

A

d) glucokinase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Where does anabolism mostly take place?

A

Cytosol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What is ATP made from?

A

Adenosine, 3 phosphate groups

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What’s the difference between ATP and GTP?

A

The nuclear base

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

High concentrations of glucose-6-phosphate is inhibitory to which enzyme?

a) Glucokinase
b) Pyruvate kinase
c)PFK
d)Hexokinase
e) Adolase

A

Hexokinase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

54) Which mineral is required for the conversion of citrate to isocitrate?

A

Iron

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

The conversion of fumarate to malate is an example of:
a) Oxidation
b) Hydration
c) Isomerisation d) Condensation e) Hydrolysis

A

Hydration

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

How many carbon dioxide molecules are produced from the complete oxidation of one glucose molecule?

A

6

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Anaplerotic reactions form intermediates of the TCA cycle. Which of these reactions is an example of an anaplerotic reaction?
a) Conversion of succinate to malate.
b) Conversionof phosphoenolpyruvate to oxaloacetate.
c) Conversion of fumarate to succinate.
d) Conversionofmalatetocitrate.
e) Conversion of citrate to fatty acids and sterol.

A

b) Conversionof phosphoenolpyruvate to oxaloacetate.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What mineral is required for the conversion of citrate into isoctirate ?

A

Iron

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What is the product of the conversion of succinyl CoA using the enzyme succinate thiokinase?
a) ATP, CoA, and succinate
b) CoA,GDP,Pi,andsuccinate
c) CoA, GTP and succinate
d) CoA,GTPandFumarate
e) Co2, NAD, H+ fumarate

A

c) CoA, GTP and succinate

17
Q

99) Which 2 amino acids are needed during growth but are not essential in later life?
a) Lysine and Arginine
b) HistidineandArginine
c) Lysine and Isoleucine
d) ArginineandIsoleucine
e) Valine and Lysine

A

B histidine and arg

18
Q

101) Which macronutrient has no form of storage in the human body to replace itself?
a) Carbohydrates
b) Lipids
c) Alcohol
d) Proteins
e) None of the above.

A

D

19
Q

108) Which organ can convert the amino groups of amino acids to urea?
a) Kidneys
b) Skeletalmuscle
c) Liver
d) Brain
e) Stomach

A

C

20
Q

In the urea cycle, when Argininosuccinate is cleaved, what does it produce?
a) Fumarate and Arginine
b) ArginineandAspartate
c) Citrulline and Fumarate
d) CarbamoylPhosphateandUrea
e) Fumarate

A

A

21
Q

118) In a regular healthy adult, a nitrogen balance is maintained. This balance is maintained by ensuring that the amount of nitrogen consumed in a person’s diet is equal to the amount of nitrogen that is excreted. Which of the following is not an example of a substance that is excreted to maintain the nitrogen balance?
a) Creatinine
b) UricAcid
c) Ammonia
d) Creatine
e) Urea

A

A - Creatine is broken down into creatinine

22
Q

The efficiency of 1g of protein, fat or carbohydrate can be ranked from highest yield in kJ to lowest. Which is the correct order?
a) Carbohydrate, Protein, Fat
b) Protein,Fat,Carbohydrate
c) Fat, Protein, Carbohydrate
d) Protein,Carbohydrate,Fat
e) Carbohydrate, Fat, Protein

A

C

23
Q

A trans fatty acid with 18 carbons is called?
a) Oleic acid
b) Palmiticacid
c) Elaidic acid
d) Arachidicacid
e) Stearic acid

A

C

24
Q

131) What is the definition of geometric isomers?
a) Structurally identical carbohydrates including the arrangement of the double bond
b) Structurallyidenticalfattyacidsexceptforthearrangementofthedoublebond
c) Structurally identical fatty acids including the arrangement of the double bond
d) Structurallyidenticalcarbohydratesexceptforthearrangementofthesinglebond
e) None

A

B

25
Q

What type of reaction is the conversion of β-ketoacyl-CoA to fatty acyl-CoA and acetyl-CoA?
a) Hydration
b) Dehydrogenation
c) Acylation
d) Dehydration
e) Thiolysis

A

C

26
Q

What does the brain and muscle tissue lack?
a) Glucose-6-phosphatase
b) Glucose
c) Glycerol
d) Ketonebodies
e) Glucose-6-phosphate

A

A

27
Q

In which part of the body does iron uptake take place?

A

Intestinal epithelial cells

28
Q

Why does glucokinase produce glucose-6-phosphate in the liver, and not hexokinase?

A

Glucokinase has a higher km than hexokinase

29
Q

What is the approximate renal threshold for plasma glucose concentration (mmol / litre)?
a) 2
b) 4
c) 6
d) 8
e) 10

A

e

30
Q

Vitamin E is a stable free radical. Which acid can reduce it to its original form?
a) Retinoic acid
b) Pantothenicacid
c) Ascorbic acid
d) Folicacid
e) Nicotinic acid

A

c

31
Q

Vitamin E is thought to protect _____ from oxidative damage?
a) Fatty acids
b) FattyacidsandapoproteinDinHDL
c) Apoproteins B in LDL
d) FattyacidsandapoproteinBinLDL
e) Apoprotein D in HDL

A

d

32
Q

Toxicity of what vitamin causes dermatitis, mucous membrane defects, hepatic dysfunction, and fracture of large bones?
a) Vitamin A
b) VitaminB
c) Vitamin C
d) VitaminD
e) Vitamin E

A

a

33
Q
A