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FMPR and INDE > FMPR 420b > Flashcards

FMPR 420b Flashcards

1
Q

Statin drug interactions

A

macrolides (erythromycin, clarithromycin) inhibit CYP34A and therefore increase statin concentration , increased likelihood of S/E

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2
Q

Antibiotics + warfarin: does the INR increase or decrease?

A

increase- risk of bleeding

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3
Q

What types of drugs can affect the QT interval?

A

antiarrhythmics, antidepressants, antipsychotics, anti-infective

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4
Q

“mitte” =

“sig”=

A 
mitte= quantity/duration of therapy
Sig= specific instructions on how to take
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5
Q

keloids more likely when you do biopsies where?

A

upper chest, deltoid

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6
Q

waist circumference targets

A

white: W< 88, M<80

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7
Q

diabetes diagnosis thresholds

A

FPG >7.0 mM
A1C> 6.5%
75 g OGTT or random PG >11.1 mM

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8
Q

gliclazide and glyburide are….

A

sulfonylureas (insulin secretagogues)

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9
Q

metformin is…

A

a biguanide (insulin sensitizer)

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10
Q

humalog is….

lantus is…

A

humalog is rapid acting

lantus is extended release..

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11
Q

BMI cut-offs

A

<18.5 underweight
18.5-24.9 normal
25-29.9 overweight
30-35 obese

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12
Q

just remember there is a difference between neuroglycopenic and neurogenic symptoms of hypoglycemia. Which comes first?

A

Neurogenic

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13
Q

What are the components of the metabolic syndrome?

A

Depends on whether it is WHO criteri or NCEP

glucose
BP
Trigs
HDL
Abdominal obesity (WC or hip:waist ratio)
ACR (part of WHO)
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14
Q

When to increase DM screening frequency?

A 
age
HTN
Hx of GDM, or macorsomic infant
ethnicity (first nations, indian, asian, african)
>abdo circumference
dyslipidemia
end organ damage
some meds
some diseases (e.g. PCOS, psych, HIV, OSA...
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15
Q

Maybe review migraine cirteria… they can last for?

A 
2 of:
unilateral
throbbing
worse on exertion
moderate to severe intensity

1 of:
photophobia +/- phonophobia
nausea +/- vomiting

Can last for 4-72 hrs

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16
Q

Triptans are contraindicated in…

A

any evidence of coronary artery disease. Use ergotamines instead?

17
Q

What is MIDAS

A

migraine disability assessment tool

18
Q

What are methods of emergency contraception and when can they be used?

A
  • Plan B (levonogestrel 0.75 mg x 1 q12h or a single dose of 1.5 mg)
  • Yuzpe (100 mcg of EE + 500 mcg of levonogestrel x 2)
  • Copper IUD

hormonal methods are effective for 5 days post intercourse, IUD is effective for 7 post-intercourse

19
Q

When are hormonal contraceptives effective after initiation of therapy?

A 
7 days (pill, patch, ring, IUS****)
OR right away if initiated on the first day of bleeding or Sunday start that falls in first 5 days
20
Q

Contraindications for OCP

A 
pregnancy
risk of thrombosis (previous DVT, FHx(?), known valvular disease)
smoker >35 y.o (>15 cig/day)
estrogen dependent cancer
sever liver disease
migraine with aura
21
Q

3 ways to start OCP

A
  • “first day start”: on 1st day of menses
  • “Sunday start”: on 1st sunday following onset of menses…don’t need back up if within 1st five days of menses
  • “quick start”: any day of the cycle- use back up for 7 days
22
Q

NYHA classification

A

1: no symptoms (but cardiac disease is known)
2: symptoms on exertion
3: symptoms with ordinary activity
4: symptoms at rest

23
Q

What is the PPS for (palliative performance scale)?

A

to assess functional capacity….

When PPS changes from the stable level of function phase (PPS 100 ->70) to the transition level of function phase (PPS 60 -> 40) the patient should be referred to the community palliative care program

24
Q

The difference between the Brief Pain Inventory and the Edmonton Symptom Assessment System (ESAS) is?

A

the Brief Pain Inventory inquires about how pain interferes with daily activities

25
Q

To convert from an oral to rectal dose using the equianalgesic dose conversion for opioids, you would….

A

…use the same dose BUT

To convert from oral to a SC or IV dose, you would use 1/3-1/2 the dose

26
Q

The CPS contains information on….

A

Discontinued products, brand and generic names, clinical information and product identification

27
Q

Acetaminophen interacts with Warfarin by….

A

interfering with the vitamin K cycle

28
Q

Post Coital IUD is most effective within ____ of unprotected intercourse but may use up to ___ post intercourse.

A

5 days, 7 days

29
Q

Is estrogen or progesterone responsible for most the the pill’s contraceptive action

A

progesterone….

30
Q

An acute complication (within two weeks) of a biopsy would be:

A

bruising

31
Q

A _______ biopsy is well suited for removing warts and molluscum and involves a partial-thickness technique.

A

curretage

32
Q

A ______ biopsy is used to obtain a sample for histopathology or fungal culture and requires local anesthetic

A

Punch

33
Q

A field block is useful to anesthetize around an abscess and involves injecting at ____ degree angles

A

90

FMPR and INDE (5 decks)

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