Fluorides Flashcards
What are the different sources of fluoride?
Diet (fis, offal and tea)
Water
Medicinal (over the counter and prescribed)
What are the benefits of water fluoridation?
1ppm has best max effects and benefits of fluoride with minimum amount of mottling
= 50% reduction in caries (esp. interproximal and smooth surface) but also a 30% reduction in pits and fissures
What is it key to remember about the best level of water fluoridation?>
1ppm eas set before fluoride containing products were so readily available therefore now a lower dose may be better
How does fluoride work?
Decreases rates of demineralisation (mainly topically), creates fluorapatite crystals (more resistant to acid erosion), some effect on bacteria
What is the critical pH?
5.5 (remineralisation) - 3.5 (demineralisation)
What is the appearance of mild fluorosis?
Diffuse flecks/patches
What is the appearance of moderate fluorosis?
mottling, striations, yellow/brown
What is the appearance of severe fluorosis?
appearance of enamel hypoplasia
What happens with too much fluoride?
- blocks cell metabolism
- interferes with calcium metabolism
- affects nerve impulses and conduction
What is acute overdose?
Fluorosis
What are the signs and symptoms of fluoride overdose?
- Vomiting, nausea, and diarrhoea
- Excessive salivation, tears, mucus and sweat
- Headache
- Generalised weakness
What dose causes lethal poisoning?
32-64 mg F/kg body weight (n.b. there have been some cases of death at 16 mg F/kg body weight)
When are you more likely to have a overdose of fluoride?
With a high dose bolus or repeated low levels
What is 1000ppm in mg F/g?
1mg F/g
What is 400ppm in mg F/g?
0.4mg F/g
What are the consequences of a toxic dose?
GI upset at approx 1mg F/kg body weight
How to deal with a fluoride overdose?
- get clear history, check dose of fluoride (package)
- Support vital signs
- management depends on dose
- drink as much milk/ milk of magnesia as possible (absorbs remaining fluoride in stomach)
How does fluorosis occur?
- affects enamel maturation (impairs mineral acquisition)
- greatest risk for centra 1’s is 15-30 months
- corral development complete at 6 y/o = less of an issue
What are the maximum doses for a 2 y/o (10kg)?
Fluoride drops = 3 ml 1mg tablets = x10 mouth rinse 0.05% = 43ml mouth rinse 0.2% = 11ml duraphat varnish = 0.43ml
What are the maximum doses for a 5 y/o (20kg)?
Fluoride drops = 5 ml 1mg tablets = x20 mouth rinse 0.05% = 86ml mouth rinse 0.2% = 22ml duraphat varnish = 0.86ml
What are the maximum doses for a 10 y/o (30kg)?
Fluoride drops = 8 ml 1mg tablets = x30 mouth rinse 0.05% = 130ml mouth rinse 0.2% = 33ml duraphat varnish = 1.3ml
What properties of the fluoride containing agents make a child more likely to overdose?
Nice colour and liquid if not secure
What do we do in the BDH for all children?
- Diet diary (sugar reducing advice)
- plaque control
- Fluoride sources (local water and provision of additional fluoride)
- Pit and fissure sealants for first permanent molars
- 2X daily toothbrushing before bed and 1 other time, supervised
What ppm fluoride toothpaste should 0-3 y/o use?
1000 ppm F toothpaste
= smear 2 x daily
What ppm fluoride toothpaste should 3+ use?
1350-1500 ppm F toothpaste
= pea sized amount 2 x daily
What % fluoride mouthwash should 6+ use? and how often should they use it?
NaF 0.05% 10ml daily
NaF 0.2% 10ml weekly