Fluids & Electrolytes Flashcards
fluid changes with age
- lose % of body wight as we age
- both sides of spectrum at risk for dehydration
- thirst drive decreases with age
osmosis
water moves from high water concentration to low water concentration
diffusion
particles move from high particle concentration to low particle concentration across semi-permeable membrane
active transport
ATP requires
Na-K pump
regulation of fluid balance
- thirst (main)
- hypothalamus
- thirst centre
antidiuretic hormone (ADH)
- opposite of diuretics; holds onto fluid
- made in hypothalamus in response to concentrated fluids —> released from pituitary and acts on renal tubules—> water reabsorbed to increase fluid volume
- opposite occurs if fluid in vascular space is dilute
nervous system regulation of fluids
baroreceptors sense change in pressure and decrease in CO —> SNS increases HR resulting in peripheral vasoconstriction —> vasoconstriction in renal arteries results in decreased glomerular filtration, decreased urine output and increased BV
increase HR for vasoconstriction to decrease urine output and increase BV
renin-angiotensin-aldosterone
- decreased BV = decreased renal perfusion = kidneys secrete renin
- renin acts on angiotensin to cause vasoconstriction = increased BP and renal perfusion
- kidneys retain Na and water increasing BV
H2O follows…
Na
cortisol
- released in stress response
- increases BG
- causes increased Na and fluid retention
- cause of fluid retention post op
kidneys
- primary organ in F&E
- adjusts urine volume to maintain balance
- urine specific gravity = hydration status
- 1.5L of urine in 24hrs
tonicity
- concentration of solutes/particles (in bag)
- determines where fluid will go
tonicity categories
- isotonic
- hypertonic
- hypotonic
isotonic IV solutions
- N/S, R/L, 2/3 & 1/3
- tonicity similar to plasma
- remains in vasculature
normal saline
0.9% NaCl
ringers lactate
closest to plasma
2/3 & 1/3
2/3 dextrose 1/3 saline
hypertonic IV solutions
- D5S, D5 1/2 N/S
- osmolality > plasma
- pulls fluid from cells into vasculature
- decreases post op edema and increase urinary output
- risk for fluid overload
- will increase BP
D5S
5% dextrose in N/S
D5 1/2 N/S
5% in 0.45% N/S
total parenteral nutrition
- TPN
- very hypertonic solution
hypotonic IV solutions
- 1/2 N/S, D5W
- osmolality < plasma
- pulls fluid from vasculature into cells/interstitial spaces
- hydrates cell while decreasing fluid in circulatory system
- risk of cardiovascular collapse as decrease volume in vessles
- risk of cells swelling and bursting (ICP)
forces within capillaries
- hydrostatic pressure
- osmotic/colloid pressure
hydrostatic pressure
- blood pumping forcing fluid/nutrients into interstitial space
- higher at arterial end
osmotic/colloid pressure
- created by plasma (albumin)
- pulls fluid from interstitial space into venous end of capillaries
- proteins pull fluid back to vessel at venous end
most common abnormal fluid shift
intravascular to interstitial space
abnormal fluid shifts
- intravascular to interstitial space
- trauma, burns, massive infection
- compression stockings