Fluids and Electrolytes Flashcards

1
Q

Nursing Care Key Highlights for Fluid & Electrolyte Imbalance

A

The nurse must anticipate potential alterations of fluid and electrolytes
Check labs and trends
Vital signs
I & O, weight
Auscultate lung sounds, heart sounds, assess for edema.
Assess heart rhythm
Ask the patient if they are experiencing any problems with breathing, chest pain, etc

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Blood is composed of:

A

Hgb and Plasma (water)

Hgb and Plasma = 100% of blood
40% Hgb + 60% Plasma = blood

If plasma decreases (dehydration), Hgb increases.
If plasma increases (fluid overload), Hgb decreases.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q
Calculation of Fluid Gain/Loss:
1 L of water = \_\_\_
240 mL (8 oz) = \_\_

A patient receiving diuretics loses 4.4 lb (2 kg). How much fluid has he lost?

A
1 L of water = 2.2lb (1 kg)
240 ml (8 oz) = 0.5 lb (0.24 kg)

ANS: approx 2L

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Weight losses of more than 1-2 lb per day is usually due to ___.

A

water loss

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

osmolality

A

measures the number of milli-osmoles per kilogram of water or the concentration of molecules per weight of water - Plasma, urine and other body fluids

Normal plasma osmolality is between 275 and 295 mOsm/kg.
> 295 = too much solute or too little water
< 275 = too little solute or too much water

Isotonic: The same osmolality as the cell interior (0.9% NS, LR)
stays in intravascular space & hydrate cells (if dehydrated)

Hypotonic (hypoosmolar): Solutions in which the solutes are less concentrated than the cells (D5W, 0.45% NS)
fluid into cells

Hypertonic (hyperosmolar): Solutions in which the solutes are more concentrated than the cells (3% Normal Saline, D5 ½ Normal saline, D5NS, D10W)
fluid out of cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

hydrostatic pressure

A

PUSH pressure

blood pressure generated by the contraction of the heart.

Allows for fluid entry at the beginning of the capillary and exit at the end of the capillary

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

oncotic pressure (colloidal osmotic pressure)

A

PULL pressure

The pressure exerted by solids. Ex. Proteins, Glucose

Water follows these large molecules

Albumin* - that’s why we give albumin with edema, it attracts the water

Diuresis with DKA*

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

ADH/Vasopressin release

A

The method by which the pituitary regulates water balance.

most important role is to conserve the fluid volume of your body by reducing the amount of water passed out in the urine

ADH released when:

  1. SIADH caused by brain tumors, brain injury, small cell lung cancer (mets)  water retention
  2. Diabetes Insipidus (suppressed ADH)
  3. Stimulates ACTH to help stimulate aldosterone secretion in adrenals
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

The adrenal cortex regulates water balance via:

A

Glucocorticoids (Cortisol)

a. Anti-inflammatories
b. Increase serum glucose

Mineralocorticoids (aldosterone)

a. Enhance Na+ retention (and thus water retention)
b. Enhance K+ excretion

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Cardiac regulation of water balance:

A

Natriuretic peptides (ANP & BNP) response to increased pressures and promote excretion of sodium and water

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

GI regulation of water balance:

A
  1. Normal water intake and output are normally between 2L & 3L per day
  2. GI tract secretes about 8L of digestive fluids each day
  3. Most reabsorbed
  4. Diarrhea or vomiting can lead to serious fluid loss
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Renal regulation of water balance:

A

Kidneys reabsorb 99% filtrate, produce around 1.5 L of urine a day

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Gerontologic considerations for water balance are:

A

i. Renal blood flow and function may be impaired or lessened
ii. Decreased Renin and aldosterone
iii. Increases in ADH and ANP
iv. Loss of subcutaneous tissue and dermis  increased loss of moisture
v. Decreased thirst
vi. Musculoskeletal changes
vii. Mental status changes
viii. Incontinence

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Fluid spacing

A

First spacing:

  1. Normal distribution of fluid in the ICF and ECF
  2. all fluid that is where it is supposed to be, including fluid inside cells and inside the blood vessels

Second spacing:

  1. abnormal accumulation of fluid of interstitial spaces (edema-varicose veins, pulmonary edema)
  2. This fluid is NOT in the cells, and NOT in the blood vessels

Third spacing:

  1. Trapping of water in areas that are non-functional and difficult to move back into cells or blood vessels (ascites, surgical shifts, burns, trauma, sepsis)
  2. Term often interchanged with edema
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Fluid shifts

A

Shifts from plasma to interstitial fluid (Edema)

Caused by

  1. Increased Plasma hydrostatic pressure
  2. Decreased Plasma oncotic pressure
  3. Decreased interstitial hydrostatic pressure (lymph blockage)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Extracellular fluid volume imbalances - nursing assessments include:

A

fluid volume deficit or excess

the nurse should assess:

  1. I&O
  2. Urine specific gravity (1.010 -1.025)
    a. Solute concentration in urine
  3. CV changes (BP, JVD, Pulse quality, lung sounds)
  4. Respiratory changes (rate, crackles, SOB)
  5. Neurologic changes (cerebral edema)
  6. Daily weights (1 kg = 1 L)
  7. Skin turgor
  8. Monitor IVs, NGs, etc.
17
Q

Fluid volume deficit

A

Causes
diarrhea, hemorrhage, polyuria, inadequate intake

Treatment
Correct underlying cause
Replace both water and electrolytes (NS, LR)
Replace blood if needed

Technically, Fluid Volume Deficit is NOT Dehydration
Dehydration = Loss of water only without sodium

18
Q

fluid volume excess

A

Causes

  1. Excessive intake (IV too fast)
  2. abnormal retention (heart failure, renal failure),
  3. fluid shifts (changes intravascular fluid)

Treatment:
Goal: To remove fluid without abnormal changes in electrolytes or osmolality (diuretics**, fluid restriction, Na+ restriction)
Thoracentesis or paracentesis if ascites or pleural effusion present

Thoracentesis – draining (with a needle) the thoracic cavity (around lungs)

Paracentesis – draining (with a needle) the peritoneum (abdomen)

19
Q

Sodium

normals and function

A

135-145

Function

  1. Plays a major role in maintaining the concentration and volume of the ECF (osmolality)
  2. Important in generation and transmission of nerve impulses
  3. Cardiac Conduction
  4. High Na is an indicator of dehydration
  5. Low Na is a cause of cerebral edema since Na can’t hold water in the vascular space.
  6. Note: high or low Na then pt will need seizure precautions
20
Q

hypernatremia

A

Causes
Increased Na intake
Increased water loss (DM, DI) – Dehydration

Leads to

a. Thirst
b. Pulls water from interstitial spaces and cells (Dehydration)  neuro changes, lethargy, agitation, seizures, coma
c. Low BP, Postural hypotension, weakness, decreased skin turgor

Treatment

a. Treat underlying cause
b. IVs (D5W, hypotonic saline)
c. Reduce Na levels gradually to prevent too rapid a shift of water back into the cells (cerebral edema)
d. Diuretics to excrete excess Na?
e. Dietary Na restriction

21
Q

hyponatremia

A

Causes

a. Loss of sodium containing fluids
b. Water excess
c. Hypotonic IV’s
d. SIADH

Leads to

a. Shift of water into cells - CEREBRAL EDEMA
b. Cardiac slowing

Treatment

a. Fluid restriction
b. Hypertonic saline (3%)

22
Q

Potassium

normals and function

A

3.5-5.0

Function

  1. 98% of K+ is intracellular
  2. Important in
    a. Neuromuscular function
    b. Cardiac function
    c. Intracellular osmolality
    d. Promotes cellular growth

Diet is the source of K+

Kidneys are primary route of K+ loss(90%)

a. Factors that cause Na retention cause K loss and vice versa
b. The ability of the kidneys to conserve K is weak even when body stores are depleted

Factors that move K into cells

a. Insulin
b. Alkalosis
c. B-Adrenergic stimulation (catecholamine release, Coronary ischemia, DT.s)
d. Rapid cell building

Factors that move K out of cells

a. Acidosis
b. Trauma
c. Exercise
d. Digoxin-like drugs
e. B-adrenergic blocking drugs (Inderal)

23
Q

hyperkalemia

A

Causes

a. Increased intake
b. Impaired renal excretion
c. Shift from inside cell
d. Blood transfusions
e. Severe infection (Acidosis -> H+ getting into cell and forcing K+ out)
f. Drugs (K sparing diuretics, ACE inhibitors)

Leads to

a. Leg cramps, weakness, paralysis
b. Bradycardias, VT, Arrest (watch peaked T waves)**
c. Abdominal cramping/diarrhea

Treatment

a. K+ restriction
b. Diuretics, dialysis, Kayexalate
c. IV insulin
d. Calcium gluconate

24
Q

hypokalemia

A

Causes

a. Abnormal losses (Kidneys or GI tract)
b. Aldosterone release (retains Na, loses K)
c. Magnesium deficiency (stimulates renin release  aldosterone release)
d. Diarrhea, laxative abuse, vomiting, ileostomy drainage
e. Metabolic alkalosis can cause a shift into the cells
f. Rapid formation of cells

Manifestations

a. Weakness or paralysis of muscles including diaphragm
b. Decreased GI motility
c. ST segment depression**
d. Ventricular dysrhythmias**

Treatment
K+ supplements - hold if UOP (urinary output) inadequate-notify the provider

25
Q

Calcium

normals and function

A

8.5-10.5

Function

  1. the most abundant mineral in the body
  2. four primary functions: making bones strong and healthy, facilitating nerve-to-nerve communication, stimulating muscle contraction, and activating blood-clotting factors.
26
Q

hypercalcemia

A

Causes

a. Hyperparathyroidism (2/3)
b. Malignancy (1/3) especially breast, lung cancers, and multiple myeloma
c. Bone destruction  increased free Ca
d. Vitamin D overdose
e. Rarely from ingestion (antacids)

Leads to

a. Reduced excitability of muscles and nerves
b. Decreased memory
c. Confusion, disorientation
d. Fatigue
e. Muscle weakness
f. Constipation
g. Cardiac dysrhythmias
h. Renal calculi

Treatment

a. **Loop diuretics (Lasix)
b. **Hydration (NS)- Increase fluid intake to 3000-4000 ml qd
c. Calcitonin (synthetic)
d. Low calcium diet
e. Mobilization with weight bearing
f. Mithracin or Pamidronate inhibits bone resorption
g. Aredia (for cancer causes) inhibits osteoclasts

27
Q

hypocalcemia

A

Causes

a. Decreased production of PTH
b. Acute pancreatitis  lipolysis  combination of fatty acids with Ca  less free Ca
c. Multiple blood transfusions
d. Sudden alkalosis
e. Decreased calcium intake
f. Increased laxative use
g. Malabsorption syndromes

Leads to

a. Increased excitability of cells  Tetany
b. Trousseau’s sign (carpal spasm by inflating a BP cuff and holding for 3 minutes)
c. Chvostek’s sign (contraction of facial muscles in response to a tap over the facial nerve in front of the ear)
d. Laryngeal stridor
e. Numbness & tingling especially around the mouth or extremities
f. Decreased cardiac contractility

Treatment

a. Treat the cause
b. Oral or IV calcium supplements (Not IM)
c. High Ca diet along with Vitamin D

28
Q

phosphate

normals and function

A

2.5-4.5

Function
build and repair bones and teeth, help nerves function, and make muscles contract, energy (ATP)

29
Q

hyperphosphatemia

A

Causes

a. Renal failure (major route for excretion)
b. Chemotherapy
c. Excessive milk intake or phosphate-containing laxatives
i. Large intake of Vitamin D  increased absorption of Phosphorus  low free calcium concentration
ii. Calcium and Phosphate usually opposite

Leads to

a. Neuromuscular irritability and tetany
b. Calcified deposits in soft tissue such as joints, arteries, skin, kidneys and corneas

Management

a. Identify and treat the underlying cause
b. Restrict foods high in phosphorus (dairy)
c. Adequate hydration
d. Correct hypocalcemia (Ca and Ph usually opposite)
e. PhosLo*

30
Q

hypophosphatemia

A

Causes

a. Malnourishment
b. Malabsorption syndrome
c. Alcohol withdrawal
d. Phosphate binding antacids
e. Parenteral nutrition with inadequate Phosphorus replacement

Manifestations

a. Impaired cellular energy and oxygen delivery
b. CNS depression, confusion, and other mental changes
c. Muscle weakness and pain, dysrhythmias, and cardiomyopathy

Management

a. Oral supplementation & ingestion of foods high in phosphorus
b. IV administration of sodium phosphate or potassium phosphate*
i. check sodium or potassium levels before giving!
ii. Ph and K have inverse relationship too
c. Watch for hypo/hypercalcemia

31
Q

Magnesium

normals and function

A

1.8-2.2

Functions:
important for many processes in the body, including regulating muscle and nerve function, blood sugar levels, and blood pressure and making protein, bone, and DNA

Mg acts directly on the myoneural junction

a. neuromuscular excitability is profoundly affected by changes in Mg levels
b. Hypermagnesemia depresses neuromuscular and CNS functions
c. Hypomagnesemia  neuromuscular and CNS hyperirritability. Can cause cardiac dysrhythmias-Torsades de pointes!**

Ca, K, and Mg should be assessed together
-All three affect cardiac dysrhythmias
-Imbalances often mistaken for Ca imbalances
-Mg and K have correlating balances
High K = low Mg, Low K = High Mg
So always check the other if one off and replace Mg first!

32
Q

hypermagnesemia

A

Cause
Occurs only with increase in intake accompanied by renal insufficiency (failure)

Manifestations

a. Lethargy, drowsiness, nausea and vomiting
b. Loss of deep tendon reflexes, somnolence, respiratory and cardiac arrest

Management

a. Prevention
b. IV Calcium chloride or calcium gluconate (Calcium gluconate is easier on pt)
c. Increase UOP (urine output) or dialysis

33
Q

hypomagnesemia

A

Causes

a. Prolonged fasting or starvation
b. Chronic alcoholism
c. Fluid loss from the GI tract  decreased absorption of Mg
d. Prolonged parenteral nutrition without Mg supplementation
e. Many diuretics**
f. High glucose levels

Manifestations

a. Confusion, hyperactive deep tendon reflexes, tremors and seizures
b. Cardiac dysrhythmias-Torsades de pointes!**
c. Clinical hypomagnesemia resemble hypocalcemia

Treatment

a. Oral supplementation/ intake - green leafy vegetables, nuts, bananas, oranges, peanut butter, chocolate
b. Parenteral IV or IM replacement for severe cases - too rapid can lead to cardiac or respiratory arrest!!