Fluids and Electrolytes Flashcards
What percentage of our body weight is water, depending on age?
60% for the average adult, 80% for an infant, and 45% for an older adult.
How much fluid in the body is extracellular?
1/3 (~15L)
How much fluid in the body is intracellular?
2/3 (~27L)
What is osmosis?
the movement of water across a semi-permable membrane from an area of high concentration to an area of low concentration.
what is diffusion?
movement of solutes from an area of high concentration to an area of low concentration.
what is active transport?
process that uses energy to move solutes from an area of low concentration to an area of high concentration
explain hydro static pressure and osmotic attraction and how they move solutes in and out of the vascular space
hydro static pressure is the force exerted on the walls of the capillaries by the blood, forcing solutes out of the vascular space. proteins are too big to cross the membrane, so they increase osmolality, pulling other materials back into the vascular space
how does damage to membranes lead to third spacing
damaged membranes are more permable and let proteins out, and therefore osmolality does not pull fluid back into the vascular space
what is the tonicity of IV fluids measured against
the osmolality (concentration of solutes) in the blood
what is an isotonic solution, and what does it do in the body?
has the same osmolality of blood, expands volume in the intravascular space
give examples of isotonic solutions
0.9% NaCL lactated ringers
who should not get ringers
pts with a ph >7.50, pts with liver disease
what is special about D5W
it is isotonic in the bag but once in the body and the dextrose is metabolized it becomes hypotonic
what is a hypotonic solution, and what does it do to the body?
osmolality is lower than blood, will push fluid into the intravascular space
give examples of hypotonic solutions
0.45 NaCl, 2.5 dextrose in 0.45 NaCl