Fluids And Electrolytes Flashcards
Total body water (TBW)
Water main component
TBW divided into intracellular water (ICW) and Extracellular water (ECW)
TBW decreases with advancing GA
First trimester - 90% of body weight
32 weeks - 80%
Term - 78%
5th month - term mostly extracellular
Age 1 - 60-65% (mostly intracellular)
Osmolality
Water’s relative content of solutes (electrolytes and proteins)
Main extracellular ion
Sodium
Regulated by kidney
Main intracellular ion
Potassium, regulated by sodium potassium cellular pump
Sodium
Major extracellular ion
Makes up 90% of total solutes in extracellular compartment
Premies dump sodium so need higher levels in bag
Potassium
Major intracellular cation
Initiates and maintains muscular contraction in cardiac and skeletal muscle
3.5-5.5
Chloride
Extracellular, works with sodium to maintain plasma volume (holds onto water)
Normal - 96-111
Low chloride and high bicarbonate - alkalosis
High chloride and low bicarbonate - acidosis
Calcium
Most abundant mineral in human body
Important for muscle contraction, neural transmission, and blood coagulation
8.8-10.3
Phosphorus
85% is in skeleton
Remaining is in soft tissues and extracellular fluid
Good for bone strength, erythrocyte function, cell metabolism, and generation and storage of energy
Milk fortification
Magnesium
Energy production, cell membrane function, and protein synthesis
1.6-2.4
Trace minerals
Zinc and copper
Zinc
Accumulated mostly in 3rd trimester
Metabolism
Copper
Adequate stores in liver for both preterm and term
Weight loss week 1 of life
5-10% in term
10-20% in preterms
Potassium in 1st DOL
Shifts from intracellular to extracellular, can rise
As renal excretion occurs will decrease
Glucose in first DOL
Decreases 60-90 minutes after birth
Once they hit low, this trigger glucogenesis ( but premies don’t have glycogen stores)
Calcium in first DOL
Abrupt stop in maternal supply, plasma will drop and reach nadir 24-48 hours after birth
PTH increases which mobilizes calcium from bone (if hypocalcemic, result of sluggish PTH response)
If lower albumin and acidosis occurs, can result in lower calcium in plasma