Fluids Flashcards
Extracellular fluid compartment
- Intravascular = fluid component of blood
- Interstitial = fluid surrounding cells 3rd spacing
- Transcellular = CSF, pericardium, synovial fluid
Principal Extracellular Fluid Electrolytes
Sodium
Bicarbonate
Chloride
Principal Intracellular Fluid Electrolytes
Potassium
Magnesium
Calcium
Intracellular Fluid (ICF) Calculations
2/3 of TBW
Extracellular Fluid (ECF) Calculations
1/3 of TBW*
a. Interstitial = 3/4 x total ECF
b. Intravascular = 1/4 x total ECF
Two factors that regulate total body volume
- Osmolality
2. Total Body Water
Baroreceptors sense change in what compartment of the body for fluid volume regulation?
Intravascular
T/F: Osmolality always overrides effective blood volume
False; Other way! (Think about Edema)
Osmolality Critical Values:
<260 =
>330 =
Must look at both serum [Osm] and ___________ in the patient to assess fluid balance.
total fluid volume
What can cause a low serum [Osm] but does not indicate excess water in the patient?
Loss of electrolytes, especially Na+
Hydrostatic pressure pushes fluids ___________ of cell and the interstitial space and ______________ of circulation. Oncotic pressure pushed fluid _________ of cells and the interstitial space and _________ of circulation.
Inside; Out
Ouside; Into
Hypovolemia
Loss of body fluid in the intrastitial and/or intravascular space
Two types of hypovolemia:
- Total body water loss
2. Intravascular hypovolemia - fluid not appropriately distributed
Symptoms of Dehydration
- Rapid weightloss (fluid v fat)
- Decreased skin turgor
- Oliguria (decreased output)
- Concentration urine
- Weak, RAPID pulse
- Decreased BP (<90/<60), orthostasis (Diastolic drop 10 mmHg; Systolic drops 20 mmHg)
- Prolonged capillary filling time - Finger nail bed test
- Sensation of thirst, weakness, dizziness, muscle cramps
Lab Findings for dehydration
- High [Osm] due to lots of fluid loss
- Low [Osm] due to lots of SODIUM loss
- Blood: High HCT, BUN:Cr ratio > 20:1
- Urine: High osmolality {>300 mOsm/kg)
How do you establish severity of dehydration?
Look at weight loss
Mild: 2%
Moderate: 6%
Severe: 10%
How do you implement fluid replacement in patients?
Must include: Maintenance + Deficit + Ongoing loss
- Replace 1/2 of deficit in the first 24 hours
- Replace remaining deficit in the next 48 hours
- Replace ongoing fluid loss mL/mL
What types of fluids can we use for fluid replacement and where do they go?
- D5W = Intravascular space; Behaves like water (Even distribution)
- 1/2 NS = Hypotonic solution acting as 1/2 free water and 1/2 NS in the body
- NS = Expands to ECF
- 3% sodium chloride
Need to increase blood pressure, which fluid replacement option would you use?
a. D5W
b. 1/2 NS
c. NS
d. 3% sodium chloride
Normal Saline due to increased fluid to interstitial space
Low blood volume and normal sodium content fluid replacement:
a. D5W
b. 1/2 NS
c. NS
d. 3% sodium chloride
a. D5W
Hypervolemia
Thirdspacing of fluid resulting in Edema and Ascities
Symptoms of hypervolemia
- Decreased output
- Increased HR
- Decreased BP
- Rapid Weight increase
- Pitting edema: Location, bilateral? and how high
- hematoma
Bilateral versus Unilateral edema
Bilateral = ORGAN FAILURE Unilateral = some other disease pathway
How do we manage hypervolemia?
- Treat underlying disease
- Restrict fluid replacement
- Administer diuretics/colloids
Best recipient of colloid infusion?
Patient with low albumin levels to increase colloid pressure