Fluid, Electrolytes, Acid Base Patho Flashcards
Capillary Hydrostatic Pressure
- Facilitates outward movement of water from capillary to interstitial space
- Blood pressure
Capillary oncotic pressure
- Osmotically attracts water from interstitial space back into capillary
Interstitial hydrostatic pressure
- Facilitates inward movement of water from interstitial space into capillary
Interstitial oncotic pressure
- Osmotically attracts water from capillary into the interstitial space
What is edema/hypervolemia?
- Excessive accumulation of fluid within interstitial space
What forces are involved with edema?
- Increased capillary hydrostatic pressure (renal failure, heart failure)
- Decreased plasma/capillary oncotic pressure (kidney disease, malnutrition, burns)
- Increased capillary membrane permeability (inflammation)
- Lymphatic channel obstruction (inflammation, cancer)
What are localized clinical manifestations of edema?
Limited to site of trauma or within particular organ system
What are generalized clinical manifestations of edema?
Uniformed distribution-dependent
What are other clinical manifestations of edema?
- Weight gain
- Swelling
- Puffiness
- Limited ROM
- Crackles
- Bounding pulse
- Could be tachycardic
How do we evaluate edema?
- History and physical
How do we treat edema?
- Treat underlying condition
- Supportive care and education
- Diet
- Diuretics
What is Clinical dehydration/hypovolemia?
Too small of a volume of fluid in the extracellular compartment (vascular and interstitial)
- Body fluids are too concentrated
What are forces of clinical dehydration?
- Fluid loss (burns, diarrhea, vomiting, blood loss, sweating, polyuria)
- Reduced fluid intake
- Fluid shifts (burns, have edema in some spaces but not in the right spaces)
Clinical Manifestations of clinical dehydration
- Tachycardia
- Poor skin turgor
- Dry mucous membranes
- No tears
- Hypotension
- Weight loss (major in peds)
- Depressed fontanels
- Decreased amount of urine (and dark color)
- Thirsty
Evaluation of clinical dehydration
- History and physical
- Labs
Treatment of clinical dehydration
- Give fluids slowly
- Stop fluid loss (treat burns, diabetes, etc)
- Is and Os are important
Sodium
- Normal level: 135-145 mEq/L
- Major ECF cation
- Acid-base balance
- Nerve conduction and neuro-muscular function
- Water balance
Hyponatremia
- Serum sodium concentration below 135 mEq/L
- ECF has too much water for amount of Na present (dilute)
- Gain of water: inappropriate fluid admin, tap water enema, excess of ADH
- Loss of salt: diuretics, renal disease, replace H2O without replacing Na
Hyponatremia Clinical Manifestations
- Nonspecific CNS dysfunction
- Malaise, anorexia, N/V, HA
- Confusion, lethargy, seizures, coma
- Fatal cerebral herniation