Fluid/Electrolytes Flashcards
Types of fluids
Blood Serum Saline Albumin Bile Urine Hormones Cerebrospinal ECF (Extracellular Fluid Volume) ICF (Intracellular Fluid Volume)
Types of hormones
Antidiuretic Hormone
Renin-Angiotensin Aldosterone System
Atrial Natriuretic Factor
Internal Body Organs
Kidneys
Heart
Lungs
Electrolytes
Charged ions capable of conducting electricity
Function of Water
Medium for metabolic reactions Lubricant Transport for nutrients, waste products Insulator Shock absorber Regulate and maintain body temp
___ % of body is water
60%
Main electrolytes in body fluid
Na+ K+ Cl- Mg 2+ Ca 2+
General Function of Electrolytes
Maintain fluid volume and concentration Distribute water between compartments Regulate acid/base balance Muscle contraction Nerve impulse transmission Blood clotting Regulate enzyme reactions (ATP)
Cations
Positively charged
Anions
Negatively charged
Normal loss of fluid and electrolytes occurs:
Urine
Stool
Sweat
Evaporation of fluid from lungs and skin (no loss of electrolytes)
Water and electrolytes can move through:
Diffusion Osmosis Facilitated diffusion Filtration Active Transport
Fluid Compartments: Extracellular
Vascular
Interstitial
Transcellular
Lymph
Diffusion
Passive movement of electrolytes or other particles down the concentration gradient (from higher to lower concentration)
**Everything but water
Facilitated Diffusion
Requires a carrier molecule
Accelerates rate of diffusion
Osmosis
Movement of water from an area of lesser to one of greater concentration through a semi-permeable membrane
**Just water
Filtration
Movement across a membrane under pressure from a higher to lower pressure
Active Transport
Movement of ions against the osmotic pressure to an area of higher pressure: requires energy
Hydrostatic Pressure
Major force that PUSHES WATER OUT of the vascular system at the capillary level and into interstitial fluid
Osmotic Pressure
INWARD PULLING force caused by particles in the interstitial and intracellular fluids
Any condition that changes osmotic pressure in either ICF or ECF compartments will cause…
Redistribution of water across semipermeable membrane
The major colloid in the vascular system contributing to the total osmotic pressure is…
protein (albumin)
Hydrostatic pressure and colloid osmotic pressure represent ____ and ____ required to _________ _________ between the _______ and _________ spaces
“push” (hydrostatic) and “pull” (Colloid Osmotic Pressure)
maintain homeostasis
interstitial and intravascular spaces
First Spacing
Normal distribution of fluid in ICF and ECF
Second Spacing
Abnormal accumulation of interstitial fluid (edema)
Third Spacing
Fluid accumulation in a part of the body where it is not easily exchanged with ECF
Plasma to interstitial fluid shift results in _____
- _______ of hydrostatic pressure
- _______ in plasma colloid osmotic pressure
- _______ of interstitial colloid osmotic pressure
Edema
Elevation
Decrease
Elevation
Interstitial fluid to plasma
Fluid drawn into plasma space with increase in plasma osmotic or colloid osmotic pressure
What can be used to decrease peripheral edema?
Diuretics and Compression stockings
What is Third space fluid shift?
Examples?
Loss of ECF into a space that does not contribute to equilibrium between ICF and ECF Severe burns Bowel obstruction Massive bleeding Ascites Peritonitis
Ascites
fluid collected within abdominal cavity is secreted by capillaries of the abdominal peritoneum
Regulation of Body Fluids
Fluid intake (Thirst mechanism) Fluid Output (Kidneys, lungs, skin, GI tract) Hormones (Aldosterone)
Tonicity of Solutions
Hypotonic 350
Fluids shift in the body to….
Expand the intravascular compartment
Expand the intravascular compartment and deplete the intracellular and interstitial compartments
Expand the intracellular compartment and deplete the intravascular compartment
Main purpose of IVFs
Replenish fluid compartments/restore balance between the ECF and ICF
Replace renal and insensible losses
Correct electrolytes
Provide glucose calories if solution contains glucose
Correct/maintain acid-base balance
IV Therapy: Isotonic Solutions
Same osmolality in relation to plasma (290)
-Matches the bodys concentration of solutes in the plasma
No fluid shifts
IV Therapy: Isotonic solutions
Action?
Examples?
Expands the bodys fluid (extracellular) volume without causing a fluid shift, replaces fluid loss, expands intravascular (plasma) volume
Examples:
NS
LR
D5W
When are isotonic solutions indicated for your patient?
When your patient has low intravascular volume from fluid loss or to dilute high concentrations of electrolytes in the serum
Isotonic solutions are best when?
You don’t want to shift fluids in or out of the cell
Isotonic solutions are given for fluid volume deficit but must be used with caution with what type of patients and why?
Heart and renal failure patients
These patients cannot handle a rapid increase in blood volume
IV Therapy: Hypotonic Solutions
Low osmolality in relation to plasma
Provides more water than electrolytes
IV Therapy: Hypotonic Solutions
Action ?
Examples ?
Dilutes the ECF and produces movement of water from the ECF to the ICF
Given to expand the intracellular space. Commonly infused to dilute extracellular fluid and rehydrate the cells of patients who have hypertonic fluid imbalances
Treat gastric fluid loss and dehydration from excessive diuresis
Examples:
2.5% Dextrose in Water
0.45% NS
5% Dextrose in 0.45%
Hypotonic solution is given to what type of patients?
Whats the goal?
Hypertonic dehydration
Water replacement
Diabetic ketoacidosis with corrected sodium level
Goal:
Pull fluid from the ECF and pull into the cell
What type of patients shouldn’t receive hypotonic solutions?
Patient with low blood pressure since it would pull the fluid dilute out the electrolytes and cause fluid to shift from the serum to the cell
(Less volume in the bloodstream = low blood pressure)
IV Therapy: Hypertonic Solution
High osmolality (concentration) in relation to plasma (>375) Fluid shifts from ICF to ECF compartments
IV Therapy: Hypertonic Solutions
Action?
Examples?
Draws water from the cells (ICF) into the vascular and interstitial spaces (ECF)
Used to treat patients who have severe hyponatremia
Examples: D5NS D5LR D10W 3% Na+ (2 nurse sign off) Colloids (Albumin 25%, dextran)
When do you give hypertonic solutions?
- When your patient has dangerously low concentrations of electrolytes or glucose
- When you want to draw fluid in from the interstitial space into the plasma
Hypertonic solutions are very ______ to veins
Irritating
How should hypertonic solutions be infused?
To prevent what?
Should be infused slowly to prevent circulatory volume overload
Summary: IVF: Isotonic
No fluid shifting
Just expands the vascular volume
Summary: IVF: Hypotonic
Shifts fluid from within the vascular space into the cells
Cells swell
Summary: IVF: Hypertonic
Shift fluid from within the cell to the vascular space
Cells shrink