Acid/Base Flashcards
Nonvolatile Acids (4)
Lactic acid: cellular death - anaerobic activity
Hydrochloric acid: stomach
Phosphoric acid: phospho-lipid
Sulfuric acid: sulfuric breakdown
Volatile Acid (1)
Carbonic acid
Buffers are substances that prevent what?
How?
Prevent major changes in pH
By releasing H+ ions
Which system gets rid of “waste” quicker?
Slower?
Respiratory (Minutes to hours)
Renal (Hours to days)
Pro and con of buffers?
React quickly
But have limited capacity to maintain pH
Main buffer is?
Bicarbonate-carbonic buffer
Other types of buffers?
Phosphate buffer system
Protein buffers
Hemoglobin
pH normal level
7.35 - 7.45
Serum bicarbonate normal level
24-28
HCO3 : H2CO3 ratio
20:1
How does respiratory maintain balance?
Increase respiratory drive to eliminate C02 when body senses acute increase in CO2
How does renal maintain balance?
Regulating HCO3 levels
Responsible for eliminating most metabolic acids
First line of defense?
Within what time period?
Action?
Buffers
Seconds
Remove or release H+
Second line of defense?
Within what time period?
Action?
Lungs
Seconds to minutes
Elimination or retention of CO2 (Hyper/hypo ventilation)
Third line of defense?
Within what time period?
Action?
Kidneys
Hours to days
Retention of HCO3, Reduction of fixed acids and elimination of H+
Acidemia is?
pH is less than 7.35
Acidosis is?
Increase in H+ (acid) or loss of base