fluid and electrolytes Flashcards
What is the name of the fluid found within the cells that constitutes 2/3 of total body fluid:
intracellular fluid
What is the fluid found outside of the cells that contains about 1/3 of the body’s total body fluid:
extracellular fluid
What are the three major compartments of the ECF:
interstitial, intravascular (plasma), transcellular fluid
What is the fluid found within the vascular system:
intravascular or plasma
What is the fluid that surrounds the cells:
interstitial fluid
What is the fluid that makes up the cerebrospinal, biliary, synovial, pleural, and peritoneal cavities:
transcellular fluid
Which of the fluids is vital for cell functioning and contains solutes: oxygen, electrolytes, and glucose which provide a medium for metabolic processes of the cell:
intracellular
Which of the fluids is the transport system that carries O2 and nutrients to and waste products from the cells:
extracellular fluid
What are some examples of cations:
Na, K, Ca, Mg
What are some examples of anions:
Cl, bicarbonate HCO3, phosphate, and sulfate
What are the principle electrolytes of the ECF:
Na, Cl, bicarbonate
What are the primary electrolytes of ICF:
K, Mg, phosphate, and sulfate
A major concern in the loss of fluids and electrolytes can occur by what causes:
vomiting, diarrhea, gastric suction
Cell membranes are permeable to what:
H2O and selectively permeable to solutes
Substances that dissolve in a liquid is defined as:
solutes
Large protein molecules that do not readily dissolve into solutions are defined as:
colloids (albumin)
The component of a solution that can dissolve a solute is defined as:
solvent
The CONCENTRATION of solutes in body fluids determined by the number of dissolved solutes per kg of water is defined as:
osmolality (mOsm/kg)
What is the primary determinant of osmolality (mOsm/kg) of plasma:
Na
What is the determinant of osmolality of ICF:
K, glucose, urea
What is the normal plasma osmolality:
280-295 mOsm/kg
A plasma osmolality that’s >295 means that the concentration is…
too great/water content too small
A plasma osmolality that’s <280 means that the concentration is…
too small/water content is too high
Isotonic, hypertonic, and hypotonic that’s used to refer to the osmolality in a solution is defined as:
tonicity
A solution that has the same osmolality as the ECF is defined as and what is an example:
isotonic; 0.9%NS/LR/D5W
A solution that has a higher osmolality than the ECF is defined as and an example is:
hypertonic; 3% NS/D5 1/2 NS/D5NS/D5LR
A solution that is less osmolality than the ECF is defined as and an example is:
hypotonic; 0.45% NS/0.33% NS/2.5 D5W
The power of a solution to pull water across a semipermeable membrane is defined as:
osmotic pressure
If I were to infuse a hypertonic solution (3% NS), what will happen to the RBCs:
Plasma will have higher concentration than the cells and will pull water from the cells–>cells will shrink
If I were to infuse a hypotonic solution (0.49 NS) into the plasma, what will happen to the RBCs:
Plasma will have less concentration causing the RBCs to pull in water from the plasma=RBCs will swell
The pulling pressure of a colloid (E.G. albumin) to pull water from the interstitial space into the vascular compartment which keeps fluid in the blood vessels is defined as:
Oncotic/colloid osmotic pressure
Movement of solutes across a membrane from higher concentration to lower concentration is defined as:
diffusion (no energy required)
Movement of WATER across a semi-permeable membrane from a lower concentration to a higher concentration is defined as:
osmosis
What happens to the concentration of plasma in a marathon runner that loses a great amount of water via sweat and how will osmosis equalize fluid balance:
Concentration in plasma is high; osmosis will cause water from the interstitial and intracellular to flow into the vascular compartment (plasma) to maintain homeostasis
The process in which both fluids and solutes move together across a membrane from high PRESSURE to low PRESSURE is defined as:
filtration (capillary fluid/nutrients seep from the arterioles to the interstitial fluid)
The (pushing) pressure exerted by a stationary fluid (fluid w/in a closed system) is defined as:
hydrostatic pressure (the force of blood exerted against the vessel walls)
The movement of solutes across a cell membrane from less concentration to greater concentration which utilizes ATP is defined as:
Active transport
What is an example of active transport:
Sodium potassium pump. K from the ECF will move into the ICF via ATP and Na from the ICF will move into the ECF via ATP
What is the primary regulator of fluid intake:
thirst mechanism located in the hypothalamus
What are some triggers of the thirst mechanism which causes the sensation of thirst:
osmotic pressure of body fluids, vascular volume, and angiotensin (released in response to decreased blood flow to the kidneys)
What organ is the primary regulator of body fluids and electrolyte VOLUME AND OSMOLALITY VIA excretion:
Kidneys
This hormone is synthesized by the hypothalamus, stored in the posterior pituitary gland, and secreted when the osmolality is high or if there’s a ECF deficit:
ADH (antidiuretic hormone)
When serum osmolality rises, what will ADH do:
ADH causes the collecting ducts to reabsorb water so that water will be absorbed into the plasma
What happens to ADH when the serum osmolality is low:
ADH is suppressed and water is excreted
What causes renin to be released and what occurs:
Decreased renal blood flow/pressure causes kidneys to release renin. Renin converts A-1 to A-2. Angio-2 causes kidneys to retain Na and H2O, and Angio-2 causes aldosterone to be sec rested from the adrenal cortex which promets Na retention. Blood volume is increased.
This hormone is released from the atrium of the heart in response to excess blood volume and stretching of the arterial walls.
Atrial Natriuretic factor (ANF)
WHy is the aterial natriuretic factor released:
Increased blood volume and stretching of the arterial walls. Acts on the kidneys as a diuretic to decrease blood volume and inhibit thirst (BP and BV is decreased)
This body system promotes return of water and protein from the interstitial spaces and into the…
lymphatic system; intravascular spaces
What is the amount of water excreted daily by a healthy person:
1000-1500 mL/day
This electrolyte is the most abundant cation of the ECF; major contributor to serum osmolality; maintains blood volume; transmits nerve impulses; contracts muscles:
Na (135-145 mEq/L)
This electrolyte is the major cation of the ICF; maintains ICF osmolality; regulates skeletal, cardiac, sm muscle activity:
K (3.5-5.1 mEq/L)
This electrolyte maintains the natural cardiac pacemaker; forms bones and teeth:
Ca (8.5-10.3 mEq/L)
This electrolyte is the second most abundant ICF cation; important for intracellular metabolism; necessary for protein/DNA synthesis w/in the ell; relaxes muscle contractions; operates Na+K pump; regulates cardiac function:
Mg (1.7-2.3 mEq/L)
This electrolyte is a major anion of the ECF; produces HCl (gastric contents); regulates ECF balance/volume; regulates acid-base balance; buffer in O2-CO2 exchange in RBCs
Cl