fluid and blood therapy 1 Flashcards

1
Q

the body is made up of __ % water

A

60

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2
Q

intracellular volume makes up __% of total body weight

A

40

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3
Q

extracellular volume makes up __% of total body weight

A

20

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4
Q

the interstitial fluid volume is part of the ___ fluid compartment

A

extracellular

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5
Q

interstitial fluid volume makes up __% of ECV, while plasma volume makes up __% of ECV

A

75, 25

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6
Q

TBW is __ % of a man’s weight

A

55

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7
Q

TBW is __ % of a woman’s weight

A

45

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8
Q

TBW is __ % of a infants weight

A

80

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9
Q

obese individuals have __ TBW per weight than non-obese

A

less

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10
Q

which three electrolytes are in the intracellular fluid compartment

A

potassium, phosphate, mag

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11
Q

sodium-potassium pump maintains the high concentration of __ in the ___

A

K in the ICF

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12
Q

how does NA +K +ATPase pump work

A

3NA+ for 2K and 1 ATP

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13
Q

ATP pump maintains high potassium __ the cell, and high sodium __ the cell

A

inside, outside

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14
Q

there is a high concentration of what two things extracellular

A

NA(cation) and Cl (anion)

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15
Q

____vascular we have a high concentration of albumin which creates osmotic pressure to hold fluids in this space

A

intra

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16
Q

normal Ca++

A

5

4.5-5.5

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17
Q

normal Mg+

A

3

1.5-2.5

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18
Q

normal Cl-

A

103

95-107

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19
Q

normal bicarb-

A

27

20-26

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20
Q

osmolarity

A

the number os osmoses of a solute in a liter of solution

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21
Q

osmolality

A

the number of osmoses of a solute in a KILOGRAM of solvent

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22
Q

how to change the osmolality?

A

change the solutes

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23
Q

isotonic solutions are approx ___ mOsm/L

A

285

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24
Q

hypovolemia is ___ but dehydration is a ____

A

fluid loss, concentration disorder

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25
Q

what is the most abundant electrolyte in the ECF

A

Na

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26
Q

most common electrolyte abnormality in hospitalized patients

A

hyponatremia

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27
Q

SIADH causes ____natremia

A

hypo

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28
Q

diuretics cause __natremia

A

hypo

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29
Q

adrenal insufficiency causes ___ natremia

A

hypo

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30
Q

vom and diarrhea causes ___ natremia

A

hypo

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31
Q

biggest risk of hyponatremia

A

cerebral edema

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32
Q

how to treat hyponatremia

A

hypertonic saline and an osmotic or loop diuretic

33
Q

Na should be corrected at what rate

A

no more than 1-2mEq/L per hr

34
Q

inadequate intake causes

A

hypernatremia

35
Q

Diabetes insipidus causes

A

hypernatremia

36
Q

normal K

A

3.5-5

37
Q

most common electrolyte abnormality encountered during clinical practice

A

hypokalemia

38
Q

Gi losses causes ___kalemia

A

hypo

39
Q

systemic alkalosis causes ___kalemia

A

hypo

40
Q

DKA causes ___kalemia

A

hypo

41
Q

diuretic therapy causes ___kalemia

A

hypo

42
Q

SNS stimulation causes ___kalemia

A

hypo

43
Q

poor dietary intake causes ___kalemia

A

hypo

44
Q

serum K <2.5 will manifest as

A

paresthesias, depressesed tendon reflexes, , fasciculation’s, muscle weakness

45
Q

EKG changes with hypokalemia

A

ST- depression, U wave, flattened or inverted T-waves, ventricular ectopy

46
Q

hypokalemia has an increased risk of myocardial irritability

A

2.6

47
Q

rate for K replacement

A

10-20 mEq/ hr

48
Q

potassium sparing diuretics causes ___kalemia

A

hyper

49
Q

metabolic or resp acidosis causes ____kalemia

A

hyper

50
Q

dig tox causes ___kalemmia

A

hyper

51
Q

insulin deficiency causes ___kalemia

A

hyper

52
Q

tissue and muscle damage after burns causes ___ kalemia

A

hyper

53
Q

succinylcholine causes ___ kalemia

A

hyper

54
Q

succs increases K by

A

.5.. even more in burn patients

55
Q

EKG changes and hyperkalemia

A

tall, peaked, and elevated T waves. widened QRS, prolonged PR. flattened or absent P wave, ST depression, cardiac arrest

56
Q

ace inhibitors, arbs, and BB cause ___ kalemia

A

hyper

57
Q

tx for hyperkalemia to shift K into the cells

A

insulin and glucose

58
Q

give IV ___ to antagonize cardiac effects of hyperkalemaia

A

Ca++

59
Q

upper limit for K for elective procedures

A

5.5

60
Q

hypomag is a serum mag less than

A

1.7 mEq/l

61
Q

Hypomag is caused by

A

inadequate dietary intake, TPN without supplementation, starvation, GI losses, chronic ETOH

62
Q

EKG changes hypomag

A

flat T waves, U waves, prolonged QT, widened QRS, PACs/PVCs

63
Q

low mag has an ____ effect on the ATP pump which alters the resting membrane potential

A

inhibitory

64
Q

IV mag dose

A

1-2g over 5min. followed by continuous Invasion 1-2g/hr.

65
Q

hyper mag is level greater than

A

2.5

66
Q

how to treat hypermg, give

A

Ca

67
Q

wht is the second messenger that couples cell membrane receptors to cellular responses

A

ca

68
Q

Mg ___ resting membrane potentials, CA ___ it.

A

decreases. increases

69
Q

hypocalcemia is caused by

A

hypoparathyroidism, malignancy, chronic renal insufficiency

70
Q

s/s of hypocalcemia neuromuscular

A

neurmusclar irritability - cramps, weakness, chvostek, trousseau, sz, numbness, tingling

71
Q

s/s of hypocalc CV

A

dysrhythmias, prolonged QT, T wave inversion, hypotension, decreased myocardial contractility

72
Q

s/s of hypocalc pulm

A

layngospasm, bronchospasm, hypovent.

73
Q

advantage of calcium chloride vs calcium gluconate

A

calcium chloride is more bioavailable and more rapid correctoin

74
Q

for every gram of calcium chloride, youd need to give how many grams of calc glu

A

3

75
Q

causes of hypercalcemia

A

hyperparathyroidism (>50% cause), tumors/malignancy, calcium mobilization from bone d/t immobility

76
Q

s/s of hypercalc cv

A

hypertension, heart block, shortened QT, dysrhythmias

77
Q

s/s of hypercalc neuromuscular

A

muscle weakness, decreased deep tendon reflexes, sedation

78
Q

tx of hypercalcemia

A

underlying cause, volume expansion with NS, loop diuretics to enhance renal excretion of Ca